Emerging Infections

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Author: Richard M. Krause
Published: December 1997
Publisher: Academic Press, Incorporated
ISBN: 0124259308
Hardcover Book
Number of Pages: 513

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Emerging Infections

Emerging Infections is the first volume of the new Biomedical Research Reports Series, which will provide annual updates on hot topics of interest to a broad spectrum of the biomedical research community. This book provides state-of-the-art reviews of new and reemerging bacterial, viral, and parasitic infections, their life cycles, host defense evasion strategies, and clinical features. It includes the history of infectious disease out-breaks, population and evolutionary biology of human pathogens, and current epidemiological models that describe how ecological and demographic changes produce new epidemics. This book presents the challenges posed by emerging infections with breadth and an informed historical perspective. Emerging Infections is a refreshing and stimulating book. This is an outstanding first volume in a new series entitled Biomedical Research Reports that contains comprehensive articles from eminent international researchers that discuss major new and reemerging pathogens. "The goal is to provide in-depth analyses of new and reemerging bacterial, viral, and parasitic infections. The state-of-the-art reviews discuss life cycles, pathogenic strategies, population and evolutionary biology, epidemiological models, and clinical features of infection. "It is written for a wide range of healthcare professionals including clinicians, clinical investigators, practitioners of public health, and microbiologists with an interest in infectious diseases. It will also be of great value to medical students, graduate students, and upper-level undergraduate microbiology students interested in the field of medical microbiology. "The volume contains seventeen review articles: an introduction; analytical theory of epidemics; tuberculosis; cholera; Escherichia coli 0157:H7; group A streptococci; lyme disease; bacterial antibiotic resistance; influenza; dengue; AIDS; hantaviral diseases; ebola; arthropod-borne pathogen; protozoa; spongiform encephalopathies; and malaria. Each topic is current and well written and has an extensive and recent list of citations. Figures and tables appropriately reinforce the text. As a whole, this volume offers a concise, detailed overview of the continuing evolution of infectious diseases. "This book is highly recommended as a comprehensive and important text for any university or departmental library collection, as well as the personal libraries of individuals who work with infectious diseases in either the research orclinical care setting. The numerous contributing authors are well regarded within their respective fields and enhance the overall value of the text. Offering some hope and an analytical theory of epidemics, Krause (National Institutes of Health, Bethesda, MD) and 28 other contributors in 17 papers respond to the challenge of stemming existing and potential epidemics. NIH's Fauci addresses the evolving threat of AIDS, while others target Dengue fever, hantaviral diseases, Ebola virus, and arthropod-borne pathogens. Revivals of tuberculosis, malaria, and streptococcal diseases are treated in light of antibiotic resistant-bacteria, and contemporary modes of transmission. 0157:H7 is elected the model of emerging infectious diseases. .

Table of Contents
1 Introduction to Emerging Infectious Diseases; Stemming the Tide 1
2 Analytical Theory of Epidemics 23
3 Persisting Problems in Tuberculosis 51
4 Mobile Genetic Elements and the Evolution of New Epidemic Strains of Vibrio cholerae 147
5 Pathogenic Escherichia coli O157:H7: A Model for Emerging Infectious Diseases 163
6 The Revival of Group A Streptococcal Diseases, with a Commentary on Staphylococcal Toxic Shock Syndrome 185
7 Lyme Disease 219
8 Antibiotic Resistance in Bacteria 239
9 Influenza: An Emerging Microbial Pathogen 275
10 The Emergence of Dengue: Past, Present, and Future 301
11 The AIDS Epidemic: Demographic Aspects, Population Biology, and Virus Evolution 327
12 Korean Hemorrhagic Fever and Hantavirus Pulmonary Syndrome: Two Examples of Emerging Hantaviral Diseases 365
13 Ebola Virus: Where Does It Come from and Where Is It Going? 375
14 Arthropod-borne Pathogens: Issues for Understanding Emerging Infectious Diseases 411
15 "New" Intestinal Parasitic Protozoa 431
16 Transmissible Spongiform Encephalopathies of Man and Animals 447
17 Malaria: A Global Threat 463
Index 499

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