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Table of Contents:

Foreword xxv
Preface xxvii
Introduction xxix
Section I. Pathogenesis
1. Autoimmunity and Autoimmune Diseases like Systemic Lupus Erythematosus
2. Overview of Cellular Immune Function in Systemic Lupus Erythematosus
3. Etiopathogenesis of Systemic Lupus Erythematosus: The Itineraries of Three Troikas
4. MHC Class II and Non-MHC Genes in the Pathogenesis of Systemic Lupus Erythematosus
5. Genetic Susceptibility and Class III Complement Genes
6. Complement Deficiency and Systemic Lupus Erythematosus
7. Gender and Age in Systemic Lupus Erythematosus
Section II. Animal Models
8. Genes and Genetics of Murine Systemic Lupus Erythematosus
9. Systemic Lupus Erythematosus in Domestic Animals
Section III. Antiantibodies and Antigens
10. Anti-DNA Antibodies: Structure, Assembly and Diversity
11. Anticytoplasmic Antibodies in SLE: Antibodies to Cytoplasmic Antigens
12. Antihistone Antibodies
13. Antibodies to Non-Histone Agents in Systemic Lupus Erythematosus
14. Immune Complexes
15. Origins of Antinuclear Antibodies
Section IV. Clinical Approach to Diagnosis
16. The Clinical Presentation of Systemic Lupus Erythematosus in Adults
17. Neonatal Lupus Syndromes
18. Systemic Lupus Erythematosus in Childhood
19. Imaging of Systemic Lupus Erythematosus: State of the Art
20. Monitoring Patients and Systemic Lupus Erythematosus
21. Laboratory Evaluation of Patients with Systemic Lupus Erythematosus
22. Systemic Lupus Erythematosus Pregnancy
23. Epidemiology of Systemic Lupus Erythematosus
24. Overlap Syndromes: Mixed Connective Tissue Disease and Sjogren's Syndrome
25. Systemic Lupus Erythematosus and Fibromyalgia
Section V. Organs Affected by Systemic Lupus Erythematosus
Nervous System
26. Neuropsychiatric Systemic Lupus Erythematosus
27. Psychiatric Aspects of Systemic Lupus Erythematosus
28. Cognitive Dysfunction in Systemic Lupus Erythematosus
Dermatology
29. Systemic Lupus Erythematosus and the Skin
Renal
30. Systemic Lupus Erythematosus and the Kidney
Cardiopulmonary
31. Cardiovascular Systemic Lupus Erythematosus
32. Systemic Lupus Erythematosus and the Cardiovascular System: Vasculitis
33. Systemic Lupus Erythematosus and the Lung
Gastrointestinal
34. Nonhepatic Gastrointestinal Manifestations of Systemic Lupus Erythematosus
35. Hepatic Disease and Systemic Lupus Erythematosus: Coincidence or Converence
Hematology
36. The Cellular Hematology of Systemic Lupus Erythematosus
Musculoskeletal
37. Articular Manifestations of Systemic Lupus Erythematosus
38. Osteoporosis and Metabolic Bone Disease in Systemic Lupus Erythematosus
Section VI. Specific Syndromes antiphospholipid Syndrome
39. Immunology of Antiphospholipid Antibodies and Co-factors
40. The Clinical Aspects of the Antiphospholipid Syndrome
41. The Catastrophic Antiphospholipid Syndrome
42. Hematology: Coagulation Problems
43. The Antiphospholipid Syndrome: Pathogenesis and Implications for Systemic Lupus Erythematosus
Drug-Induced Systemic Lupus Erythematosus
44. Pathophysiology of Drug-Induced Systemic Lupus Erythematosus
45. Drug and Environmental Systemic Lupus Erythematosus: Clinical Manifestations and Differences
Section VII. Therapy of Systemic Lupus Erythematosus
46. Corticosteroid Use in Systemic Lupus Erythematosus
47. Antimalarials and Immunosuppresive Therapies
48. Unproven and Experimental Therapies
Index 1317