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Contributors
Preface
Acknowledgment
1 Introduction: An Overview of the Mucosal System
2 Structure and Function of Intestinal Mucosal Epithelium
3 Cellular and Molecular Basis for Antigen Transport in the Intestinal Epithelium
4 Mucosal Barrier
5 Innate Humoral Factors
6 Bacterial Adherence and Mucosal Immunity
7 Mucosal Immunoglobulins
8 Phylogenetic Aspects of Mucosal Immunoglobulins
9 Developmental Aspects of Mucosal Immunoglobulin Genes: Organization and Expression of IgA Heavy-Chain, Polymeric Immunoglobulin Receptor, and J-Chain Genes
10 Epithelial and Hepatobiliary Transport of Polymeric Immunoglobulins
11 Function of Mucosal Immunoglobulins
12 Characteristics and Functions of Mucosa-Associated Lymphoid Tissue
13 Peyer's Patches as Inductive Sites for IgA Commitment
14 Regulation of IgA B Cell Development
15 Diversity and Function of Antigen-Presenting Cells in Mucosal Tissues
16 Oral Tolerance and Regulation of Immunity to Dietary Antigens
17 Functional Aspects of the Peptidergic Circuit in Mucosal Immunity
18 The Role of B-1 Cells in Mucosal Immune Responses
19 Lymphocyte Homing to Mucosal Effector Sites
20 Cytokines in the Mucosal Immune System
21 Distribution and Characteristics of Mucosal Immunoglobulin-Producing Cells
22 T Helper Cells for Mucosal Immune Responses
23 Human Gastrointestinal Mucosal T Cells
24 Basic Aspects of Intraepithelial Lymphocyte Immunobiology
25 IgE-Mediated Responses in the Mucosal Immune System
26 Inflammation: Mast Cells
27 Cytokines in the Liver and Gastrointestinal Tract
28 Cytotoxic Lymphocytes in Mucosal Effector Sites
29 Mucosal Immunity to Viruses
30 Passive Immunization: Systemic and Mucosal
31 Common Mucosal Immune System and Strategies for the Development of Vaccines Effective at the Mucosal Surfaces
32 Antigen Delivery Systems: New Approaches to Mucosal Immunization
33 Mucosal Adjuvants
34 Monoclonal Secretory IgA for Protection of the Intestinal Mucosa against Viral and Bacterial Pathogens
35 Gut-Associated Lymphoid Tissue
36 Alpha Chain Disease and Related Lymphoproliferative Disorders
37 Gastritis and Peptic Ulcer
38 The Role of the Mucosal Immune System in Ulcerative Colitis and Crohn's Disease
39 Malabsorption Syndromes and Intestinal Protein Loss
40 Food Allergy
41 Intestinal Infections
42 Liver and Biliary Tract
43 Bronchial Mucosal Lymphoid Tissue
44 Mucosal Immune Function in Asthma
45 Respiratory Infections
46 Inhalant Allergy and Hypersensitivity Disorders
47 Ocular Mucosal Immunity
48 Mucosal Immunology of the Middle Ear and Eustachian Tube
49 Immunology of Diseases of the Oral Cavity
50 Immunobiology of the Tonsils and Adenoids
51 Immunological Components of Milk: Formation and Function
52 Immunologic Effects of Breast-Feeding on the Infant
53 IgA Nephropathy and Related Diseases
54 Mucosal Immunity in the Female and Male Reproductive Tracts
55 Immunologically Mediated Male and Female Reproductive Failure
56 Endocrine Regulation of Mucosal Immunity: Effect of Sex Hormones and Cytokines on the Afferent and Efferent Arms of the Immune System in the Female Reproductive Tract
57 Mucosal Immunopathophysiology of HIV Infection
58 Genital Tract Infection: Implications in the Prevention of Maternal and Fetal Disease
Index