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Foreword
Preface
Abbreviations
1 A Brief History of Neuroimmunology 3
2 A Review of the Immune System 69
3 Immunologic Principles Related to the Nervous System and the Eye: Concerning the Existence of a Neural-Ocular Immune System 99
4 Cervical Lymphatics, the Blood-Brain Barrier, and Immunoreactivity of the Brain 134
5 Microglia and Macrophages 155
6 Astrocytes: Normal Aspects and Response to CNS Injury 173
7 Lymphocyte Entry and the Initiation of Inflammation in the Central Nervous System 200
8 Innervation of Lymphoid Organs and Neurotransmitter-Lymphocyte Interactions 226
9 Autoantigens of the Nervous System 333
10 Antigen Presentation in the Central Nervous System 364
11 Cytokine Expression in the Nervous System 419
12 CD4 Effector Cells in Autoimmune Diseases of the Central Nervous System 460
13 Direct Cell-Mediated Responses in the Nervous System: CTL vs. NK Activity, and Their Dependence Upon MHC Expression and Modulation 493
14 Neuroendocrine-Immune Interactions 548
15 Establishment and Control of Viral Infections of the Central Nervous System 576
16 Transplantation into the Central Nervous System 611
17 Immunosuppression: CNS Effects 642
18 Immunology of the Eye 668
19 Autoimmune Demyelinating Diseases of the Central Nervous System 703
20 AIDS and the Nervous System 727
21 Tumors of the Central Nervous System 760
22 Immunology of the Peripheral Nervous System 785