Hematology

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Author: William S. Beck
Published: August 1991
Publisher: MIT Press
ISBN: 0262521571
Paperback Book
Number of Pages: 667

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Hematology

The fifth edition of this well-known series of lectures by distinguished Harvard hematologists is substantially revised to include discussions of the many important scientific developments in contemporary hematology. New insights into oncogenes, growth factors, membrane receptors, differentiation and morphogenesis, enzymology, molecular biology, and evolutionary biology appear in virtually every lecture. A lecture on general principles of malignant disease appears for the first time in recognition of the fact that in many hospitals and medical schools hematology departments now encompass oncology - an important topic that is not covered elsewhere in the medical curriculum.

This new edition also adds many tables and figures relating to differential diagnosis that will be useful to practicing physicians and house officers. Examples include causes of splenomegaly, indications for splenectomy, differential diagnosis of normocytic anemia, macrocytic anemia, hypochromic anemia, thrombocytopenia, bone marrow failure syndromes, and many others. The bibliographies have been expanded, a new appendix containing laboratory methods has been added, and there is an unusually complete index.

William S. Beck has taught the hematology courses at Harvard for many years. He is Professor of Medicine at the Harvard Medical School, Director of the Hematology Research Laboratory at the Massachusetts General Hospital, Professor at the Harvard-NUT Division of Health Sciences and Technology, and Tutor in Biochemical Sciences at Harvard College. The fifth edition of this well-known series of lectures by distinguished Harvard hematologists is substantially revised to include discussions of the many important scientific developments in contemporary hematology. The latest revision of Beck's renowned syllabus (1st edition, 1973; 4th, 1985) finds it somewhat redesigned to better serve as a reference for house officers and practicing physicians, although its primary audience remains first and second year medical students. Among the substantive changes are added discussions of the myeloid growth factors, erythropoietin, the red cell cytoskeleton, oncogenes, and newer aspects of immunology, hemato-oncology, and clotting.

Table of ContentsPreface to the Fifth Edition
From the Introduction to the First Edition
Contributors
1 Hematopoiesis
William S. Beck
2 Erythropoiesis and Introduction to
Anemias
William S. Beck
3 Reticuloendothelial (Mononuclear Phagocyte)
System, Lymphatic System, and Spleen
William S. Beck
4 Normocytic Anemias
William S. Beck
5 Megaloblastic Anemias I. Cobalamin
Deficiency
William S. Beck
6 Megaloblastic Anemias II. Folic Acid
Deficiency
William S. Beck
7 Hypochromic Anemias I. Iron Deficiency and
EXcess
William S. Beck
8 Hypochromic Anemias II. Heme Metabolism and
the Porphyrias
Stephen H. Robinson
9 Hemoglobin I. Structure and Function
H. Franklin Bunn
10 Hemoglobin II. Sickle Cell Anemia and Other
Hemoglobinopathies
H. Franklin Bunn
11 The Thalassemias
David G. Nathan
12 Hemolytic Anemias I. Introduction
W. Hallowell Churchill, Jr., and James H. Jandl
13 Hemolytic Anemias II. Immunohemolytic
Anemias
W. Hallowell Churchill, Jr., and James H. Jandl
14 Hemolytic Anemias III. Membrane
Disorders
William S. Beck and Robert I. Tepper
15 Hemolytic Anemias IV. Metabolic
Disorders
William S. Beck and Robert I. Tepper
16 Blood Groups I. Chemistry and
Physiology
W. Hallowell Churchill, Jr.
17 Blood Groups II. Transfusion Therapy
W. Hallowell Churchill, Jr.
18 Leukocytes I. Physiology
William S. Beck
19 Leukocytes II. Phagocytosis and its
Disorders
Thomas P. Stossel
20 Introduction to the Disorders of
Leukocytes
William S. Beck
21 Malignant Disease: Some General
Principles
Stuart E. Lind
22 The Leukemias
David C. Harmon
23 The MalignantLymphomas I. Clinical
Aspects
David S. Rosenthal
24 The Malignant Lymphomas II. Pathology
Nancy L. Harris
25 Plasma Cell Disorders and the
Dysproteinemias
W. Hallowell Churchill, Jr.
26 The Polycthemias
William B. Castle
27 Hemorrhagic Disorders I. Protein Interactions
in the Clotting Mechanism
Robert D. Rosenberg
28 Hemorrhagic Disorders II. Platelets
David J. Kuter
29 Hemorrhagic Disorders III: Disorders of
Hemostasis
David J. Kuter and Robert D. Rosenberg
AppendiX: Laboratory Methods in Hematology
Alice Weaver Flaherty
IndeX

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