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Combination Therapies: Biological Response Modifiers in the Treatment of Cancer and Infectious Diseases

Author: Allan L. Goldstein
Published: October 1993
ISBN: 0306445891
Hardcover Book
Number of Pages: 266
 
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Combination Therapies: Biological Response Modifiers in the Treatment of Cancer and Infectious Diseases


Table of Contents:


1 Cytokine Synergy in Immunotherapy 1
2 Monitoring Combination Therapy Trials: New Challenges for the Clinical Laboratory 11
3 IL-2-Based Consolidative Immunotherapy After Autologous Bone Marrow Transplantation 23
4 Tumor Immunogenicity Induced by the Local Occurrence of IL-2 31
5 Thymosin [alpha][subscript 1]: Chemistry, Mechanism of Action and Clinical Applications 39
6 Combination Therapy with Thymosin [alpha][subscript 1] and Cytokines in the Treatment of Cancer and Infectious Diseases 49
7 Effect of Thymosin [alpha][subscript 1] on Cocaine-induced Inhibition of T-Cell Dependent Murine Immune Response 61
8 Regulation of Gene Expression by Interferons 67
9 Interactions Between Tumor Necrosis Factor Alpha and Glucocorticoid Hormones in the Regulation of Tumor Cell Growth In Vitro 71
10 Behavioural, Pyrogenic and Electrocortical Effects of Tumor Necrosis Factor-Alpha Given Intracerebrally in Rats 81
11 Biological Significance and Therapeutic Potential of Tumor-Associated Leukocytes 87
12 Septic Shock Pathophysiology: Focus on Therapeutic Approach 95
13 Differentiating Agents and Cancer Therapy. Role of Cellular Lipid Peroxidation and its Product 4-Hydroxynonenal in the Control of Cell Proliferation and Differentiation 105
14 Inhibition of HIV Replication and Enhancement of Immune Functions by the Acyclic Nucleoside Phosphonate 9-(2-Phosphonyl-Methoxyethyl) Adenine (PMEA)
15 Modulation of Inflammatory Cytokines by a Receptor Antagonist, Autoantibodies, and Fever 123
16 Cancer Immunochemotherapy: Preliminary Studies with Triazene Compounds 135
17 Thymosin [alpha][subscript 1] and [alpha]-Interferon with Cisplatin and Etoposide in Advanced Non-Small Cell Lung Cancer: A Phase II Study 149
18 Combination of Chronic Indomethacin and Intermittent IL-2 Therapy in the Treatment of Disseminated Cancer 155
19 Combination Chemotherapy and Cytokines in the Treatment of Advanced Primary Lung Cancer: Results of a Controlled Clinical Trial 167
20 Biological Response Modifiers and Differentiating Agents in Myelodisplastic Syndromes
21 Myeloid Growth Factors in Cancer Treatment 179
22 Efficacy of the Combined Treatment with Fluconazole and Thymosin [alpha][subscript 1] Against Candida albicans Infection in Morphine-Treated Mice 189
23 Anti-Cytokine Therapy of Murine Candidiasis 195
24 The Basic Research and Clinical Application of Thymopeptidin 201
25 Treatment of Hepatitis C Virus-Associated Chronic Liver Disease with [beta]-Interferon and Inosine Pranobex: Combination Schedule vs. Monotherapies 209
26 Sustained Response to Thymosin Therapy in Patients with Chronic Active Hepatitis B 219
27 Combination Anti-HIV Therapy: Questions and Answers 225
28 Mechanisms of Disease Progression and CD4 Depletion in HIV-1 Infection 229
29 Combined Therapy with Zidovudine, Thymosin [alpha][subscript 1] and [alpha]-Interferon in the Treatment of HIV-Infected Patients
30 The Problem of Interferon Species Appearing in Patients with Autoimmune Diseases 243
Index 251


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Combination Therapies: Biological Response Modifiers in the Treatment of Cancer and Infectious Diseases





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