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1 Stress and Disease: The Contribution of Hans Selye to Psychoneuroimmunology. A Personal Reminiscence 1
2 Histamine, Capsaicin and Neurogenic Inflammation. A Historical Note on the Contribution of Miklos (Nicholas) Jancso (1903-1963) to Sensory Pharmacology 17
3 Neural Regulation of Allergy and Asthma. The Discoveries and Seminal Contributions of Andor Szentivanyi 25
4 The Immune-Neuroendocrine Circuitry - The Next, and Possibly, the Last Frontier of Vertebrate Immunity 41
5 Neuroendocrine Control of the Thymic Microenvironment: Role of Pituitary Hormones 75
6 Immunomodulation by Growth Hormone in Humans 83
7 Insulin-like Growth Factors and Immunity: An Overview 99
8 Prolactin as an Immunomodulatory Hormone 111
9 Prolactin and Autoimmunity: Influences of Prolactin in Systemic Lupus Erythematosus 125
10 Effects of Cytokines on the Hypothalamo-Pituitary-Adrenal Axis 137
11 The Role of Cytokines in Immune Neuroendocrine Interactions 149
12 Cytokines and Sleep Mechanisms 161
13 Interleukin Involvement in the Regulation of Pituitary Cell Growth 173
14 Lipid Saturation in the Target Cells Plasma Membrane Blocks Tumor Necrosis Factor Mediated Cell Killing 181
15 Bidirectional Communication Between the Immune and Endocrine Systems - Mediation by Hormones from the Gonads 191
16 Glucocorticoid Regulation of Mucosal Immunity: Effect of Dexamethasone on IgA and Secretory Component (SC) 203
17 Androgen Regulation of Ocular Mucosal- and Auto-Immunity 213
18 Immunoregulation by Sex Hormone Analogues 223
19 Tamoxifen as an Immunomodulating Agent 233
20 Neuroendocrine-Immune Interactions in Pituitary Pathology 243
21 Endocrine-Immune Interactions in the Gastrointestinal Tract 253
22 Substance P, Immunity and Inflammation of the Intestinal Mucosa 263
23 Expression of Cholinergic Structure on Lymphocytes 271
24 Regulation of NK Cells During Acute Physiological Stress by Noradrenaline 279
25 Psychological and Neural Regulation of Intestinal Hypersensitivity 291
26 The Cervical Sympathetic Trunk-Submandibular Gland Axis in the Regulation of Inflammatory Responses 303
27 Neuroendocrine Aspects of Lymphocyte Migration 317
28 Mechanisms of Stress-Induced Host Defense Alterations 323
29 Plasticity of Neuroendocrine-Immune Interactions During Aging 331
30 Beta-Endorphin in Peripheral Blood Mononuclear Cells: Effects of Aging and Pharmacological Treatments 339
31 The Role of the Adrenergic/Cholinergic Balance in the Immune-Neuroendocrine Circuit 349
Index 357