Helicobacter Pylori Infection and Immunity

Author: Yoshimasa Yamamoto
Published: December 2001
Publisher: Kluwer Academic Publishers
ISBN: 0306466589
Hardcover Book
Number of Pages: 286

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Surveys the current status of immunologic, microbiologic, and therapeutic prevention studies on the human pathogen H. pylori, which has been linked with gastric cancer. The 15 chapters describe diagnostic tests for detecting infection, the risk factors and pathology of peptic ulcers, eradication therapy, and the effects of antibiotics. Other contributions discuss natural substances with anti-H. pylori activity, how the microorganism binds to gastric cells, the involvement of H. pylori in autoimmune diseases, the effects of toxins from the organism on host cells, animal models for infection studies, and the development of a vaccine against Helicobacter.

Table of Contents:

Introduction and Perspectives
1 The Bacteriology of Helicobacter pylori
2 Diagnosis of Helicobacter pylori Infection
3 Helicobacter pylori Infection and Gastric Cancer
4 Risk Factors and Peptic Ulcer Pathology
5 Helicobacter pylori Eradication Therapy
6 Mechanisms of Antibiotic Resistance in Helicobacter pylori
7 Anti-Helicobacter pylori Activity of Natural Substances
8 Adherence of Helicobacter pylori to Gastric Cell
9 Helicobacter pylori, Molecular Mimicry and Autoimmunity
10 Apoptosis and the Pathogenesis of Helicobacter pylori - Related Disease
11 Toxins, Travels and Tropisms: H. pylori and Host Cells
12 Role of Cytokines in Helicobacter pylori Infection
13 Animal Models for Helicobacter pylori
14 Mongolian Gerbils Model
15 Vaccine Development
Index

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