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Preface
1 Carbohydrate Blood Group Antigens and Tumor Antigens 1
2 Structural Basis for Mannose-Binding Protein Function in Innate Immunity 34
3 C-Reactive Protein: Structure, Synthesis and Function 46
4 Complement: A Major Humoral Effector System in Innate and Acquired Immunity 62
5 Carbohydrate Recognition Receptors on Antigen Presenting Cells 74
6 Toll-Like Receptor: Specificity and Signaling 87
7 C-Type Lectin and Lectin-Like Receptors in the Immune Systems 101
8 The Sialic Acid-Binding Siglec Family 119
9 Antibody Responses to Polysaccharides 128
10 CD1-Restricted T Cell Responses against Microbial Glycolipids 148
11 Processing and Presentation of Glycoproteins in the MHC Class I and II Antigen Presentation Pathways 173
12 Chemical Synthesis of Bacterial Carbohydrates 192
13 Challenges and Opportunities in the Development of New Conjugate Vaccines against Infectious Diseases 274
14 Carbohydrate-Based Targets and Vehicles for Cancer and Infectious Diseases Vaccines 292
15 The Interaction between Anti-Gal and the [alpha]-Gal Epitope As an Immunologic Barrier to Xenotransplantation 302
Index 313