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Table of Contents:

Preface
Contributors
Sect. 1 Physiology of Aging
Invited Commentary 3
1 Cell and Molecular Aging 8
2 Demography of Aging; Comparative, Differential, and Successful Aging; Geriatric Assessment 24
3 Cancer, Carcinogenesis, and Aging 38
4 Effects of Aging on Immune Function 46
5 Nutrition, Metabolism, and Wound Healing in the Elderly 65
Sect. 2 Surgical Management of the Elderly Patient
Invited Commentary 89
6 Principles of Geriatric Surgery 92
7 Aging of America: Implications for the Surgical Workforce 105
8 Should Surgery Be Rationed for the Elderly on Cost-Effectiveness Grounds? 111
9 Interacting with the Elderly Patient, Family, and Referring Physicians 118
10 Preoperative Evaluation of the Elderly Surgical Patient 126
11 Anesthetic Considerations for Geriatric Surgery 144
12 Pain Management 160
13 Drug Usage in Elderly Persons 174
14 Postoperative Outcome and Rehabilitation 185
Sect. 3 Ethical Considerations
Invited Commentary 193
15 Ethics in Clinical Practice 195
16 Surgery in the Frail Elderly: Nursing Home Patients 202
17 Surgery in Centenarians 211
Sect. 1 Critical Care and Trauma
Invited Commentary 221
18 Critical Care 225
19 Care of the Injured Elderly 240
Sect. 2 Endocrine System
Invited Commentary 263
20 Endocrinology and Aging 265
21 Surgical Diseases of the Thyroid and Parathyroid Glands 281
22 Neoplasms of the Adrenal and Endocrine Pancreas in the Elderly 301
Invited Commentary 323
23 Physiologic Changes and Benign Perimenopausal Breat Disease 325
24 Breast Cancer in Elderly Women 331
Sect. 3 Eyes, Ears, Nose, and Throat
Invited Commentary 345
25 Pathogenesis and Surgical Management of Common Geriatric Ophthalmic Disorders 348
26 Physiologic Changes in the Ears, Nose, and Throat 368
27 Head and Neck Cancer in the Elderly 376
Sect. 4 Respiratory System
Invited Commentary 393
28 Physiologic Changes in Respiratory Function 396
29 Pulmonary Malignancies: Pathophysiology and Treatment 406
Sect. 5 Cardiovascular System
Invited Commentary 435
30 Physiologic Changes in Cardiac Function with Aging 437
31 Risk Factors for Atherosclerosis in the Elderly 448
32 Cardiac Surgery in the Elderly 460
Invited Commentary: Vascular System 471
33 Surgical Treatment of Occlusive Vascular Disease in the Elderly 475
34 Natural History and Treatment of Aneurysms 485
35 Natural History and Treatment of Extracranial Cerebrovascular Disease in the Elderly 497
Sect. 6 Gastrointestinal System
Invited Commentary: Gastrointestinal System 509
36 Age-Related Physiologic Changes in the Gastrointestinal Tract 511
37 Benign Esophageal Disease in the Elderly 528
38 Esophageal Cancer in the Elderly 542
39 Pathophysiology and Treatment of Benign Diseases of the Stomach and Duodenum 555
40 Small Bowel Obstruction in the Elderly 569
41 Lower Gastrointestinal Bleeding in the Elderly 580
42 Ischemic Disorders of the Large and Small Bowel 595
43 Inflammatory Bowel Disease in the Elderly 609
44 Diverticulitis and Appendicitis in the Elderly 620
45 Benign Colorectal Disease 635
46 Neoplastic Diseases of the Colon and Rectum 644
47 Abdominal Wall Hernia in the Elderly 662
Sect. 7 Hepatobiliary System
Invited Commentary 677
48 Hepatobiliary and Pancreatic Function: Physiologic Changes 679
49 Gallstone Disease in the Elderly 690
50 Malignant Diseases of the Gallbladder and Bile Ducts 711
51 Benign and Malignant Tumors of the Liver 729
52 Pancreatitis in the Elderly 740
53 Pancreatic Tumors: Pathophysiology and Treatment 748
Sect. 8 Urogenital System
Invited Commentary 763
54 Renal Function and Fluid and Electrolyte Balance 767
55 Urinary Incontinence in the Elderly 780
56 Renal and Bladder Neoplasms in the Elderly 790
57 Benign and Malignant Diseases of the Prostate 806
58 Benign Gynecologic Disorders in the Elderly 817
59 Gynecologic Malignancies in the Elderly 834
Sect. 9 Soft Tissue and Musculoskeletal System
Invited Commentary 847
60 Physiologic Changes in Soft Tissue and Bone as a Function of Age 850
61 Common Benign and Malignant Skin Lesions 867
62 Orthopedic Injuries 885
63 Joint Replacement in the Elderly Patient 900
Sect. 10 Nervous System
Invited Commentary 923
64 Effects of Aging on the Human Nervous System 926
65 Benign and Malignant Tumors of the Brain 949
66 Spinal Disorders and Nerve Compression Syndromes 957
Sect. 11 Transplantation
Invited Commentary 985
67 Selection of Elderly Patients for Transplantation 989
68 Transplantation in Elderly Patients 995
Sect. 12 Applications of Minimal Access Techniques to the Surgical Case of the Elderly
69 Physiology of Laparoscopic Surgery 1021
70 Outcomes of Minimal Access versus Open Surgical Procedures in the Elderly 1036
Index 1055