Clinical Hematology and Oncology: Presentation, Diagnosis, and Treatment

Author: Bruce Furie
Published: July 2003
Publisher: Elsevier Science
ISBN: 044306556X
Hardcover Book
Number of Pages: 955

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After noting that hematology and oncology have become integrated disciplines, Furie (Harvard Medical School) and contributors from many leading US cancer centers discuss cancer symptoms by bodily system and related blood chemistry abnormalities. They also treat evaluation and treatment, supportive care for patients, genetic counseling, alternative medicine, psychological, and other issues. Chapters cover risk factors and preventive measures for specific cancers, and diagnostic and treatment guidelines. Color plates illustrate the range of cancer symptoms and hematological indicators.

Table of Contents
Contributors
Preface
Contents
1 Weight Loss and Anorexia 3
2 Fever of Unknown Origin 9
3 Pruritus 14
4 Headache 19
5 Seizures 23
6 Cranial Neuropathy 27
7 Encephalopathy and Neuropathy 32
8 Neck Mass 43
9 Hoarseness 50
10 Palpable Breast Masses 59
11 The Abnormal Mammogram 65
12 Nipple Discharge 71
13 Dyspnea 75
14 The Solitary Pulmonary Nodule 81
15 Pleural Effusion 87
16 Hilar and Mediastinal Adenopathy 94
17 Superior Vena Cava Syndrome 98
18 Hemoptysis 106
19 Bowel Obstruction 109
20 Focal Liver Lesions 115
21 Ascites 128
22 Splenomegaly 135
23 Dysphagia 139
24 Gastrointestinal Bleeding 144
25 Pathologic Fractures 149
26 Back Pain 156
27 Renal and Adrenal Masses 165
28 Hematuria 173
29 Testicular Mass 179
30 Vaginal Bleeding 184
31 Hypercalcemia 191
32 Elevated Bilirubin 196
33 Immunoglobulin Abnormalities 200
34 Iron Studies: Normal and Abnormal 207
35 Lymphadenopathy 213
36 Thrombocytopenia and Thrombocytosis 221
37 Anemia 232
38 Quantitative Abnormalities of Leukocytes 241
39 Pancytopenia 251
40 Erythrocytosis 256
41 Bleeding Disorders 265
42 Morphologic Abnormalities of the Peripheral Blood 272
43 Venous Thromboembolic Disease 283
44 Cutaneous Manifestations of Bleeding and Thrombotic Disorders 293
45 Pigmented Skin Lesions 305
46 Cancer of Unknown Primary 313
47 Radiation Oncology 321
48 Cancer Chemotherapy 330
49 Surgical Oncology 362
50 Biologic Therapy 376
51 Hematopoietic Stem Cell Transplantation 391
52 Growth Factors 419
53 Transfusion Medicine 431
54 Bone Marrow Failure Syndromes 443
55 Red Blood Cell Disorders 455
56 White Cell Disorders 475
57 Platelet Disorders: Acquired and Congenital 485
58 Coagulation Disorders: Acquired and Congenital 498
59 Venous Thromboembolism 511
60 Acute Myeloid Leukemia 521
61 Acute Lymphoblastic Leukemia 549
62 Myelodysplasia 566
63 Multiple Myeloma, Macroglobulinemia, and Amyloidosis 581
64 Diagnosis of Malignant Lymphoma and Hodgkin's Disease 601
65 Hodgkin's Disease 615
66 Low-Grade Non-Hodgkin's Lymphoma 636
67 Intermediate- and High-Grade Lymphoma 648
68 Extranodal Non-Hodgkin's Lymphoma 660
69 Peripheral T Cell Lymphomas 664
70 Adult T Cell Leukemia/Lymphoma 672
71 Chronic Myeloid Leukemia 676
72 Chronic Lymphocytic Leukemia and Hairy Cell Leukemia 688
73 Polycythemia Vera, Idiopathic Myelofibrosis and Essential Thrombocythemia 701
74 Breast Cancer - Staging and Prognosis 715
75 Noninvasive Breast Cancer 726
76 Locally Invasive Breast Cancer 737
77 Metastatic Breast Cancer 750
78 Breast Cancer: Supportive Measures and Follow-up Care 763
79 Carcinoma of the Cervix, Vulva, and Vagina 769
80 Endometrial Cancer 782
81 Ovarian Cancer 791
82 Trophoblastic Tumors 804
83 Testicular Germ Cell Cancer 813
84 Renal Cancer 825
85 Superficial Bladder Cancer 842
86 Muscle-Invasive Bladder Cancer 850
87 Prostate Cancer 859
88 Esophageal Cancer 875
89 Gastric Cancer 887
90 Hepatobiliary Cancers 899
91 Pancreatic Cancer 908
92 Colorectal Cancer 921
93 Anal Carcinoma 938
94 Small Cell Lung Cancer 943
95 Non-Small Cell Lung Cancer 958
96 Thymoma 983
97 Mesothelioma 991
98 Primary Head and Neck Cancer 999
99 Second Primary Cancers of the Head and Neck 1012
100 Salivary Gland Carcinoma 1017
101 Bone Sarcomas 1027
102 Soft-Tissue Sarcomas 1038
103 Primary Brain Tumors 1049
104 Brain Metastases 1062
105 Epidural Tumors and Spinal Cord Compression 1077
106 Melanoma 1085
107 Nonmelanoma Skin Cancer 1104
108 Thyroid Cancer 1117
109 Adrenal Cancer 1129
110 Neuroendocrine Cancer 1133
111 Pituitary Cancer 1139
112 Cancer of Unknown Primary 1147
113 Cancer and the Immunocompromised Host 1155
114 Hematologic Manifestations of Cancer 1166
115 Febrile Neutropenia 1173
116 Thromboembolic Manifestations of Cancer 1179
117 Tumor Lysis Syndrome 1187
118 Screening and Genetic Counseling for the Patient with Cancer 1193
119 Unorthodox Approaches to Cancer Therapy 1209
120 Psychosocial Issues 1224
121 Sexual Dysfunction 1235
122 Symptom Management 1240
Index 1261

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