Search for the best prices     on the Internet!

Foreword
List of Contributors
Ch. 1 Pharmacological Significance of Nicotine 1
Ch. 2 Biosynthesis of Nicotine and Related Compounds 13
Ch. 3 Biotransformation of Nicotine in Mammalian Systems 45
Ch. 4 Chemical Properties of Nicotine and Other Tobacco-Related Compounds 69
Ch. 5 The Physical Chemistry of Nicotine 149
Ch. 6 Use of Gas Chromatographic and Mass Spectrometric Techniques for the Determination of Nicotine and its Metabolites 191
Ch. 7 Use of High-Performance Liquid Chromatographic-Mass Spectrometric (LC-MS) Techniques for the Determination of Nicotine and its Metabolites 225
Ch. 8 Use of Immunoassay Techniques for the Determination of Nicotine and its Metabolites 265
Ch. 9 Determination of Nicotine in Tobacco, Tobacco Processing Environments and Tobacco Products 285
Ch. 10 Determination of Nicotine in Pharmaceutical Products and Dietary Sources 393
Ch. 11 Nitrosamines Derived from Nicotine and Other Tobacco Alkaloids 421
Ch. 12 Determination of Nicotine in Mainstream and Sidestream Cigarette Smoke 489
Ch. 13 Nicotine in Environmental Tobacco Smoke 531
Ch. 14 Determination of Nicotine and its Metabolites in Biological Fluids: in vivo Studies 583
Ch. 15 Determination of Nicotine and its Metabolites in Biological Fluids: in vitro Studies 645
Ch. 16 Uses and Abuses of Cotinine as a Marker of Tobacco Smoke Exposure 669
Subject Index 721