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This book summarises these; the important practical aspects in diagnosis, differential diagnosis and treatment of diabetic nephropathy based on current knowledge. Aspects of pathogenesis and clinical features for specific groups such as pregnant women, adolescents and patients with cardiovascular complications and disorders of lipid metabolism are also covered.An area of great importance and interest to both clinicians in diabetes and the health care teamA practical clinical approachContributions from experts with considerable experience of treating patients with these complications Diabetic Nephropathy will provide the reader with a solid grounding in the current basic and clinical research in this area.

Table of Contents:

List of Contributors
Preface
Pt. I Natural Course, Pathogenesis, Morphology and Genetics 1
1 Diabetic Nephropathy - the Size of the Problem 3
2 Natural Course of Diabetic Nephropathy 19
3 Pathogenesis of Diabetic Nephropathy: Biochemical and Functional Alterations of Glomerular Basement Membrane and Mesangium 39
4 Pathogenesis of Diabetic Nephropathy: Haemodynamic Alterations 59
5 Renal Structural Damage in IDDM and NIDDM - Functional Relationships 71
6 Diabetic Nephropathy in Children and Adolescents 91
7 Genetic Predictors and Markers of Diabetic Nephropathy 103
Pt. II Clinical Problems and Concomitant Diseases 115
8 Screening for and Diagnosis of Incipient Diabetic Nephropathy (IDN) in Diabetes 117
9 Differential Diagnosis of Proteinuria in Diabetic Patients 129
10 Hypertension in Diabetic Nephropathy 145
11 Cardiovascular Complications in Proteinuric Diabetic Patients 155
12 Lipid Disorders in Diabetic Nephropathy 175
13 Eye Complications in Diabetic Nephropathy 193
14 Pregnancy and Diabetic Nephropathy 203
Pt. III Treatment and Prognosis 221
15 Effect of Glycaemic Control on the Development and Progression of Diabetic Nephropathy 223
16 Blood Pressure Control in Hypertensive Diabetic Patients with Proteinuria 237
17 Early Antihypertensive Intervention in Diabetic Patients with Incipient Nephropathy 257
18 Dietary Modifications in Patients with Diabetic Nephropathy 265
19 Training of Patients with Diabetic Nephropathy 277
20 Endstage Renal Failure in Diabetes Mellitus: Special Problems of Treatment and Monitoring 283
21 Prognosis of Patients with Diabetic Nephropathy 297
Index 309