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Table of Contents:

Contributors
Preface
1 A Short History of Renal Transplantation 1
2 Immunobiology of Organ Transplantation 7
3 Immune Response in Pediatric Renal Transplantation 17
4 Immunosuppressive Strategies for the Pediatric Population 23
5 Cross-Match Considerations in Organ Transplantation 51
6 Major Histocompatibility Complex in Human Transplantation 69
7 Preemptive Transplantation 87
8 Influence of Histocompatibility Testing on Allograft Outcome 95
9 Pretransplantation and Posttransplantation Psychosocial Evaluation 109
10 Live Related Kidney Donation 137
11 Live Unrelated Donor Transplantation 145
12 Prognostic Factors for Cadaver Donor Kidney Transplantation in Children 157
13 Impact of Recipient Age on Renal Allograft Outcome 165
14 Surgical Technique 187
15 Maintenance Immunosuppression Regimens 201
16 Adequate Levels of Long-Term Immunosuppression in Pediatric Kidney Transplant Patients 211
17 Steroid Withdrawal After Renal Transplantation 221
18 Postoperative Management of Pediatric Transplant Patient 239
19 Diagnosis and Treatment of Postoperative Allograft Dysfunction 257
20 Diagnosis of Acute Rejection 269
21 Treatment of Acute Rejection 279
22 OKT3 in Pediatric Renal Transplantation 291
23 Management of Hypertension Posttransplantation 307
24 Complications of Cyclosporine 315
25 Urologic Complications in Renal Transplantation 337
26 Transplantation in Primary Hyperoxaluria 349
27 Management of the Child With Congenital Nephrotic Syndrome 379
28 Management of Cystinosis 387
29 Noncompliance to Medical Regimens 397
30 Pubertal Development After Renal Transplantation 409
31 Growth Posttransplantation in Children: Steroids and Growth Inhibition 423
32 Use of rhGH Posttransplantation in Children 441
33 Malignancy in Children 461
34 Pregnancy in the Renal Allograft Recipient Transplanted During Childhood 471
35 Renal Transplantation in Children: The North American Pediatric Renal Transplant Cooperative Study (NAPRTCS) Experience 481
36 Recurrent Primary Disease and De Novo Nephritis Following Renal Transplantation 503
37 Long-Term Outcome of Kidney Transplantation in Children 525
Index 535