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Growth Factors as Drugs for Neurological and Sensory Disorders: Symposium, Vol. 196

Author: Jack Kessler
Published: September 1996
Publisher: Wiley, John & Sons, Incorporated
ISBN: 0471957216
Hardcover Book
Number of Pages: 253
 
Click to compare book prices for Growth Factors as Drugs for Neurological and Sensory Disorders: Symposium, Vol. 196
Growth Factors as Drugs for Neurological and Sensory Disorders: Symposium, Vol. 196


Degeneration of sensory receptors or of the nerves innervating them leads to a sensory deficit. Various strategies have been tried for promoting regrowth of sensory receptors, particularly in the eye and ear. The latest data from experimental studies in animals are presented in the book including applications of BDNF and CNTF in the eye and epidermal growth factor in the ear.


Table of Contents:


Introduction 1
Motor neuron disease and model systems: aetiologies, mechanisms and therapies
Potential utility of rhIGF-1 in neuromuscular and/or degenerative disease 18
Therapeutic potential of the neurotrophins and neurotrophin-CNTF combinations in peripheral neuropathies and motor neuron diseases 39
Development of neurotrophic factor therapy for Alzheimer's disease
Growth factor function in the development and maintenance of midbrain dopaminergic neurons: concepts, facts and prospects for TGF-[beta] 70
Somatic gene therapy for nervous system disease 85
Neurotrophic factors in the treatment of peripheral neuropathy 108
Growth factors in the treatment of degenerative retinal disorders 120
Effects of neurotrophins on the survival and regrowth of injured retinal neurons 144
Neurotrophic factors as pharmacological agents for the treatment of injured auditory neurons 149
Growth factors as potential drugs for the sensory epithelia of the ear 167
Factors affecting neuronal birth and death in the mammalian olfactory epithelium 188
The problems of delivering neuroactive molecules to the CNS 211
Closing remarks 240
Index of contributors 241
Subject index 243


Click to compare book prices for Growth Factors as Drugs for Neurological and Sensory Disorders: Symposium, Vol. 196
Growth Factors as Drugs for Neurological and Sensory Disorders: Symposium, Vol. 196





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