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Cancer Vaccines and Immunotherapy

Author: Peter L. Stern
Published: July 2000
Publisher: Cambridge University Press
ISBN: 0521622638
Hardcover Book
Number of Pages: 296
 
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Cancer Vaccines and Immunotherapy


Rapid progress in the definition of tumor antigens, and improved immunization methods, bring effective cancer vaccines within reach. In this wide-ranging survey, leading clinicians and scientists review therapeutic cancer vaccine strategies against a variety of diseases and molecular targets. Intended for an interdisciplinary readership, their contributions cover the rationale, development and implementation of vaccines in human cancer treatment, with specific reference to cancer of the cervix, breast, colon, bladder, and prostate, and to melanoma and lymphoma. They review target identification, delivery vectors and clinical trial design. The book begins and ends with lucid overviews from the editors, that discuss the most recent developments.

CONTRIBUTORS: 1. Immunity and cancer Peter Beverley, Miles Carroll and Peter L. Stern 2. Immunotherapy of bladder cancer Anton B. Alexandroff and Keith James 3. Poxviruses as vectors for cancer immunotherapy Miles Carroll and Nicholas P. Restifo 4. Vaccina-based human papilloma virus vaccines Leszek K. Borysiewicz and Stephen Man 5. Vaccine delivery and immuno suppression in cervical cancer Michael P. Rudolf, Laurie A. Small, Markwin P. Velders, Diane M. DaSilva, Sanne Weijzen and W. Martin Kast 6. Vaccines for colon cancer Howard L. Kaufman and Jeffrey Schlom 7. Muci vaccines and breast cancer Joyce Taylor-Papadimitriou, Joy Burchell and David W. Miles 8. Anti-idiotypic vaccination Lindy G. Durrant, Ian Spendlove and R. Adrian Robins 9. Immunotherapy and vaccination against EpsteinĀ­Barr virus-associated cancer John R. Arrand 10. Serologically identified tumour antigens as cancer vaccines Ugur Sahin, "Ozlem T"ureci and Michael Pfreundschuh 11. CTL-defined cancer vaccines in melanoma and other epithelial cancers Elke J"ager, Dirk J"ager and Alexander Knuth 12. DNA vaccines against B-cell tumours Freda K. Stevenson, Delin Zhu, Myfanwy Spellerberg, Catherine A. King, Surinder S. Sahota, Jason Rice, Andrew R. Thompsett and Terry J. Hamblin 13. Dendritic cell approaches to immunotherapy Malcolm Adams, Bharat Jasani, Camilo A. L. S. Colaco and Malcolm D. Mason 14. Overview and recent developments Peter L. Stern, Peter Beverley and Miles Carroll Index.


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Cancer Vaccines and Immunotherapy





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