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Table of Contents:

Contributing Authors
Preface to First Edition
Preface
Acknowledgments
Sect. 1 History 1
1 Historical Development of Cardiopulmonary Bypass in Minnesota 3
2 The Birth of an Idea and the Development of Cardiopulmonary Bypass 22
Sect. 2 Equipment 35
3 Blood Pumps 37
4 Principles of Oxygenator Function: Gas Exchange, Heat Transfer, and Operation 49
5 Circuitry and Cannulation Techniques 69
6 Cardiotomy Suction and Venting 98
7 Hemofiltration, Dialysis, and Blood Salvage Techniques During Cardiopulmonary Bypass 105
8 Circulatory Assist Devices: Applications for Ventricular Recovery or Bridge to Transplant 131
Sect. 3 Physiology and Pathology 147
9 Blood-Surface Interface 149
10 Pulsatile Cardiopulmonary Bypass 167
11 Hemodilution and Priming Solutions 186
12 Hypothermia: Physiology and Clinical Use 197
13 Surgical Myocardial Protection 214
14 Changes in the Pharmacokinetics and Pharmacodynamics of Drugs Administered During Cardiopulmonary Bypass 265
15 Immune and Inflammatory Responses After Cardiopulmonary Bypass 303
16 Embolic Events 320
17 Endocrine, Metabolic, and Electrolyte Responses 342
18 Cardiopulmonary Bypass and the Lung 367
19 Cardiopulmonary Bypass and the Kidney 382
20 Splanchnic, Hepatic, and Visceral Effects 391
21 Neurologic Effects 403
Sect. 4 Hematology 433
22 Anticoagulation for Cardiopulmonary Bypass 435
23 Heparin Neutralization 473
24 Hematologic Effects of Cardiopulmonary Bypass 492
25 Management of Coagulopathy Associated with Cardiopulmonary Bypass 506
26 Blood Transfusion and Blood Conservation 534
Sect. 5 Clinical Applications 547
27 Conduct of Cardiopulmonary Bypass 549
28 Management of Unusual Problems Encountered in Initiating and Maintaining Cardiopulmonary Bypass 578
29 Termination of Cardiopulmonary Bypass 613
30 Cardiopulmonary Bypass in Infants and Children 633
31 Extracorporeal Membrane Oxygenation for Respiratory or Cardiac Support 662
32 Extracorporeal Cardiopulmonary Support for Resuscitation and Invasive Cardiology Outside the Operating Suite 696
33 Noncardiovascular Applications of Cardiopulmonary Bypass 704
34 Perfusion for Thoracic Aortic Surgery 724
35 Cardiopulmonary Bypass for Port-Access Cardiac Surgery 736
Subject Index 753