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Foreword to the Fourth Edition
Foreword to the First Edition
Preface to the Fourth Edition
Preface to the First Edition
Contributing Authors
Ch. 1 Embryology and Structure of the Kidney 3
Ch. 2 The Renal Circulation 43
Ch. 3 Glomerular Filtration 56
Ch. 4 Determinants of the Glomerular Filtration of Macromolecules 61
Ch. 5 The Neural Control of Renal Function and Extracellular Fluid Volume 65
Ch. 6 General Principles of Renal Tubular Transport 70
Ch. 7 Renal Handling of Organic Compounds 70
Ch. 8 Urinary Concentration and Dilution 104
Ch. 9 Renal Cell Metabolism 110
Ch. 10 Physiology of Ureter, Bladder, and Urethra 122
Ch. 11 Renal Growth and Hypertrophy 130
Ch. 12 Role of the Kidney in Hormone Metabolism 141
Ch. 13 Kidney and Endocrine System 151
Ch. 14 Body Fluid Compartments 233
Ch. 15 Water and Sodium Metabolism 248
Ch. 16 Potassium Homeostasis 276
Ch. 17 Calcium Metabolism 308
Ch. 18 Magnesium Metabolism 341
Ch. 19 Phosphate Metabolism 355
Ch. 20 Acid-Base Metabolism 380
Ch. 21 Renal Actions and Use of Diuretics 444
Ch. 22 Idiopathic Edema 457
Ch. 23 Defects of Renal Tubular Transport 462
Ch. 24 Fluid and Electrolyte Disorders in Infants and Children 477
Ch. 25 Oliguria and Anuria 489
Ch. 26 Polyuria and Nocturia 493
Ch. 27 Dysuria and Frequency 500
Ch. 28 Hematuria and Pigmenturia 503
Ch. 29 Renal Colic and Flank Pain 513
Ch. 30 The Renal Mass 518
Ch. 31 Edema 526
Ch. 32 Proteinuria 545
Ch. 33 Hypertension 550
Ch. 34 Uremia 555
Ch. 35 General Concepts of Immunopathology 565
Ch. 36 Immune Mechanisms of Glomerular and Vascular Diseases 568
Ch. 37 Role of Mediator Systems in Glomerular and Vascular Diseases 589
Ch. 38 Immunopathogenesis of Tubulointersitial Diseases 639
Ch. 39 Glomerular Diseases 649
Ch. 40 Tubulointerstital Nephropathies 746
Ch. 41 Renal Infectious 759
Ch. 42 Renal Involvement in Multisystem Diseases 777
Ch. 43 Renal Involvement in Heredofamilial and Congenital Disease 844
Ch. 44 Gout and Renal Disease 869
Ch. 45 Diabetic Nephropathy 874
Ch. 46 Cystic Diseases of the Kidney 896
Ch. 47 Nephropathies Due to Drugs, Chemicals, or Physical Agents 912
Ch. 48 Acute Renal Failure Including Cortical Necrosis 956
Ch. 49 Metabolic and Endocrine Abnormalities in Acute Renal Failure 978
Ch. 50 Obstructive Nephropathy 986
Ch. 51 Renal Papillary Necrosis 1004
Ch. 52 Occlusive Renal Vascular Disease 1011
Ch. 53 Nephrolithiasis 1017
Ch. 54 Tumors of the Kidney and Urinary Tract 1039
Ch. 55 Effects of Heart and Liver Disease and Neoplasia on Kidney and Electrolyte Metabolism 1063
Ch. 56 Kidney in Nutritional Disorders 1082
Ch. 57 The Kidney and Aging 1094
Ch. 58 Kidney Diseases and Hypertension in Pregnancy 1106
Ch. 59 Pathophysiology of Essential Hypertension 1121
Ch. 60 Genetics of Hypertension 1136
Ch. 61 Essential Hypertension 1141
Ch. 62 Renovascular Hypertension 1159
Ch. 63 Endocrine Hypertension 1169
Ch. 64 Pediatric Hypertension 1184
Ch. 65 Geriatric Hypertension 1190
Ch. 66 Hypertension in African-Americans 1196
Ch. 67 Progression of Renal Insufficiency 1203
Ch. 68 Uremic Toxicity 1221
Ch. 69 Central and Peripheral Nervous System in Uremia 1279
Ch. 70 Cardiovascular System in Uremia 1292
Ch. 71 Pulmonary Complications of Uremia 1314
Ch. 72 Hematopoietic System in Uremia 1318
Ch. 73 Gastrointestinal Tract in Uremia 1330
Ch. 74 Metabolic and Endocrine Disturbances in Uremia 1342
Ch. 75 The Skin in Uremia 1377
Ch. 76 Disturbances in Fluid, Electrolyte, and Acid-Base Balance 1381
Ch. 77 Divalent Ion Metabolism and Renal Osteodystrophy 1394
Ch. 78 Uremic Myopathy 1426
Ch. 79 Articular Complications in Uremia 1430
Ch. 80 Immunological Disturbances in Uremia 1433
Ch. 81 Cancer in Uremia 1439
Ch. 82 Appetite in Chronic Renal Failure 1443
Ch. 83 Nutritional Management 1449
Ch. 84 Dialysis Therapy 1474
Ch. 85 Drugs in Renal Failure 1564
Ch. 86 Immunology and Genetics of Transplantation 1604
Ch. 87 Selection and Preparation of Donors and Recipients for Renal Transplantation 1611
Ch. 88 Renal Allograft Dysfunction 1617
Ch. 89 Complications of Renal Transplantation 1652
Ch. 90 Renal Transplantation in Specific Diseases 1689
Ch. 91 Renal Transplantation in Children 1702
Ch. 92 Outcome of Renal Transplantation 1711
Ch. 93 Xenotransplantation of the Kidney 1721
Ch. 94 Hemodialysis and Hemoperfusion in the Management of Drug Intoxication 1729
Ch. 95 Plasmapheresis 1736
Ch. 96 Renal Biopsy 1742
Ch. 97 Use of the Urethral Catheter 1747
Ch. 98 Bone Biopsy 1751
Ch. 99 Shock-Wave Lithotripsy 1758
Ch. 100 Urinalysis 1765
Ch. 101 Quantitative and Qualitative Measurements of Urinary Protein 1784
Ch. 102 Biochemical Investigations of Urine 1787
Ch. 103 Evaluation of Renal Function 1793
Ch. 104 Assessment of Renal Anatomy and Function with Radionuclides 1805
Ch. 105 Magnetic Resonance Imaging of the Kidney 1812
Ch. 106 Diagnostic Use of Ultrasound in Kidney and Bladder 1820
Ch. 107 Computed Tomography of the Kidney and Urinary Tract 1857
Ch. 108 Radiology of the Kidney 1884
Ch. 109 Atlas to Renal Pathology 1947
Index 1999