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Table of Contents:

Contributors
Preface
1 Introduction 3
2 Trial Design and Conduct 7
3 Interpreting a Trial Report 33
4 Limitations of Clinical Trials 43
5 Ethical Issues in Randomized Clinical Trials 73
6 Lipid-lowering Agents 87
7 Dietary Fat Intake 103
8 Hypertension 115
9 Aspirin, Heparin, and Fibrinolytic Therapy for Acute Coronary Syndromes without ST Elevation 161
10 Coronary Bypass Surgery 173
11 Interventional Cardiology 185
12 Coronary Angioplasty and Coronary Artery Bypass Surgery 203
13 Thrombolysis 221
14 Antiplatelet and Anticoagulant Therapy 241
15 ACE Inhibitors in and after Myocardial Infarction 261
16 Beta-blockers, Calcium Blockers, Nitrates, and Magnesium in and after Myocardial Infarction 271
17 Antiarrhythmic Treatment Strategies 291
18 Heart Failure 309
19 Rehabilitation 355
Index 379