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The sixth edition (2000) is recommended for a minimum core collection by Brandon/Hill. The two volumes of the 7th contain 66 chapters by kidney specialists--most from the US, but quite a few from countries including Israel, France, Lebanon, The Netherlands, Canada, Brazil and the Czech Republic. The first 17 chapters in volume one address the elements of normal renal structure and function. The remaining chapters cover disturbances in control of body fluid volume, pathogenesis and pathophysiology of renal disease, and management of patients with renal failure. Topics include nutritional therapy in renal disease; transplantation immunobiology; cardiovascular aspects of chronic kidney disease; renal neoplasia, laboratory assessment of kidney disease; adaptation to nephron loss; effects of aging on renal function and disease; and specific pharmacologic approaches to clinical renoprotection.

Table of Contents:

1 Anatomy of the Kidney 3
2 Developmental Biology of the Kidney 73
3 Biology of Renal Cells in Culture 105
4 Cell-Cell and Cell-Matrix Interactions 199
5 The Metabolic Basis of Solute Transport 231
6 The Molecular Basis of Solute Transport 261
7 The Renal Circulations 309
8 Glomerular Ultrafiltration 353
9 Renal Transport of Glucose, Amino Acids, Sodium, Chloride, and Water 413
10 Control of Renal Potassium Excretion 453
11 Renal Acidification Mechanisms 497
12 Renal Transport of Calcium, Magnesium, and Phosphate 535
13 The Cell Biology of Vasopressin Action 573
14 Urine Concentration and Dilution 599
15 Renal Handling of Organic Anions and Cations: Excretion of Uric Acid 637
16 Vasoactive Peptides and the Kidney 663
17 Arachidonic Acid Metabolites and the Kidney 727
18 Control of Extracellular Fluid Volume and the Pathophysiology of Edema Formation 777
19 Pathophysiology of Water Metabolism 857
20 Acid-Base Disorders 921
21 Disorders of Potassium Balance 997
22 Clinical Disturbances of Calcium, Magnesium, and Phosphate Metabolism 1041
23 Approach to the Patient with Kidney Disease 1079
24 Laboratory Assessment of Kidney Disease: Clearance, Urinalysis, and Kidney Biopsy 1107
25 Interpretation of Urine Electrolyte and Acid-Base Parameters 1151
26 Radiologic Assessment of the Kidney 1183
27 Acute Renal Failure 1215
28 Primary Glomerular Disease 1293
29 Secondary Glomerular Disease 1381
30 Tubulointerstitial Diseases 1483
31 Urinary Tract Infection, Pyelonephritis, and Reflux Nephropathy 1513
32 Disorders of the Renal Arteries and Veins 1571
33 Microvascular Diseases of the Kidney 1601
34 Toxic Nephropathy 1625
35 The Kidney and Hypertension in Pregnancy 1659
36 Inherited Disorders of the Renal Tubule 1697
37 Cystic Diseases of the Kidney 1743
38 Diabetic Nephropathy 1777
39 Nephrolithiasis 1819
40 Urinary Tract Obstruction 1867
41 Renal Neoplasia 1895
42 Renal and Systemic Manifestations of Glomerular Disease 1927
43 Adaptation to Nephron Loss 1955
44 Biology of the Vascular Wall in Hypertension 1999
45 Essential Hypertension 2023
46 Renovascular Hypertension and Ischemic Nephropathy 2065
47 Hypertension and Renal Disease 2109
48 Pathophysiology of Uremia 2139
49 Hematologic Consequences of Renal Failure 2165
50 Cardiovascular Aspects of Chronic Kidney Disease 2189
51 Neurologic Complications of Renal Insufficiency 2227
52 Renal Osteodystrophy 2255
53 Effects of Aging on Renal Function and Disease 2305
54 Diuretics 2345
55 Antihypertensive Drugs 2381
56 Specific Pharmacologic Approaches to Clinical Renoprotection 2453
57 Nutritional Therapy in Renal Disease 2491
58 Erythropoietin Therapy in Renal Disease and Renal Failure 2539
59 Hemodialysis 2563
60 Peritoneal Dialysis 2625
61 Intensive Care Nephrology 2697
62 Extracorporeal Treatment of Poisoning 2733
63 Transplantation Immunobiology 2759
64 Donor and Recipient Issues in Renal Transplantation 2785
65 Clinical Aspects of Renal Transplantation 2805
66 Prescribing Drugs in Renal Disease 2849
Index