Joint Disease in the Horse

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Author: C. Wayne McIlwraith
Published: January 1996
Publisher: Saunders W B Co
ISBN: 0721651356
Hardcover Book
Number of Pages: 490

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Joint Disease in the Horse

This text is arranged in five sections with a total of 29 authors. The sections cover the general principles of joint pathobiology and the pathology, pathogenesis, and diagnosis of traumatic and degenerative joint disease. Other sections cover treatment, osteochondrosis, and current research. Its purpose is to bring together current material in the field of joint diseases in the horse. It will make a useful study as well as reference text for practitioners and students. The book is designed to be of value to both researchers and clinicians. The book is illustrated with mostly high-quality black-and-white photographs and diagrams. The references are presented with each of the 29 chapters and are a valuable source for additional reading material. This book is well organized, and the authors are to be congratulated on producing a valuable addition to the libraries of equine clinicians, research workers, and veterinary students. The material present covers a wide field but, by necessity, each section or chapter is of itself only the essence of the subject. For example, the chapters on imaging techniques and surgical treatment are forced to be brief. These problems are, however, offset to some degree by the inclusion with each chapter of extensive reference lists to direct the reader to additional current resources. In general, the illustrations are of good quality, although not all of the radiographs reproduced with acceptable clarity. The surgical treatment section might have been improved with color illustrations of some of the arthroscopic lesions. The four chapters devoted to current research relevant to equine joint disease give an excellent review of cellular and receptormechanisms in joint disease. In other chapters, nutritional, genetic, and conformational influences on joint pathology are reviewed but are not pulled into the current research sections. This book will prove to be a valuable and extremely useful resource for all veterinarians who work with horses and is strongly recommended. McIlwraith, C. Wayne, BVSc, MS, PhD, Dr med vet (Colorado State Univ); Trotter, Gayle W., DVM, MS (Colorado State Univ)The contributors represent the specialties of veterinary surgery, anatomy, physiology, cell biology, and radiology. Most come from veterinary medicine colleges in the U.S., the U.K., France, Canada, and Australia. Institutions prominently represented include Cornell, Michigan State, Ohio State, Colorado State, UC Davis, Univ of London, and McGill.

Table of Contents
Ch. 1 Anatomy and Physiology of Synovial Joints 1
Ch. 2 Articular Cartilage Homeostasis and the Role of Growth Factors and Cytokines in Regulating Matrix Composition 29
Ch. 3 General Pathobiology of the Joint and Response to Injury 40
Ch. 4 Neurogenic Factors in Joint Pain and Disease Pathogenesis 70
Ch. 5 Functional Joint Anatomy and Its Development 80
Ch. 6 Pathologic Manifestations of Joint Disease in the Athletic Horse 87
Ch. 7 Joint Biomechanics in the Pathogenesis of Traumatic Arthritis 104
Ch. 8 Clinical Features and Diagnosis of Equine Joint Disease 120
Ch. 9 Imaging Techniques in the Diagnosis of Equine Joint Disease 145
Ch. 10 Ultrasonographic Examination in the Diagnosis of Joint Disease 165
Ch. 11 Use of Synovial Fluid and Serum Markers in Articular Disease 203
Ch. 12 Rest, Exercise, and Physical Therapy Programs 217
Ch. 13 Nonsteroidal Anti-inflammatory Drugs 223
Ch. 14 Intra-articular Corticosteroids 237
Ch. 15 Hyaluronan and Its Use in the Treatment of Equine Joint Disease 257
Ch. 16 Polysulfated Glycosaminoglycan (Adequan) 270
Ch. 17 Potential Use of Pentosan Polysulfate for the Treatment of Equine Joint Disease 281
Ch. 18 Surgical Treatment of Joint Injury 292
Ch. 19 Joint Resurfacing: Attempts at Repairing Articular Cartilage Defects 317
Ch. 20 Pathogenesis of Equine Osteochondrosis 335
Ch. 21 Pathogenesis of Osteochondrosis - Genetic Implications 359
Ch. 22 Clinical Aspects of Osteochondritis Dissecans 362
Ch. 23 Subchondral Cystic Lesions in Horses 384
Ch. 24 Infectious Arthritis 397
Ch. 25 Other Conditions Affecting Equine Joints 410
Ch. 26 Animal Models and Other Experimental Systems in the Investigation of Equine Arthritis 421
Ch. 27 Isolated Chondrocyte and Cartilage Explant Culture Systems as Techniques to Investigate the Pathogenesis of Equine Joint Disease 441
Ch. 28 Cellular Responses and Receptor Mechanisms in Joint Disease: A Bacterial Lipopolysaccharide-Induced Model of Articular Damage 447
Ch. 29 Arthritis Research: Some Present and Future Directions in Joint Disease 468
Index 475

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