Biological and Clinical Basis of Infectious Diseases

Author: Stanford T. Shulman
Published: January 1997
Publisher: Saunders W B Co
ISBN: 0721659489
Paperback Book
Number of Pages: 643

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This is the fifth edition of a book that initially was developed as a reference source for medical students during infectious disease elective rotations. If the intended audience remains those students, this edition is justified. The authors have attempted to update recent new advances and place them in the context of the clinical disease itself. It is suitable for the medical student in infectious diseases rotations and, perhaps, first- or second-year housestaff. The book suffers from lack of depth in almost all chapters. There is one very unfortunate chapter title that appears to link the chronic fatigue syndrome to viral infections of the upper respiratory tract. This most likely inadvertent granting of legitimacy to a viral causation theory is regrettable. The individual chapters have subheadings of content within the chapter listed below the title. Some readers may like this; others may find it unnecessary. In the fungal infection chapter, where all subcomponents for each disease are the same, tighter editorial corrections would have helped. Readers beyond the level of medical student may want to seek greater in-depth information in several of the comprehensive infectious disease texts recently published. Shulman, Stanford T., MD (Northwestern Univ); Phair, John P., MD (Northwestern Univ); Peterson, Lance R., MD (Northwestern Univ); Warren, John R., MD (Northwestern Univ)The contributors represent the specialties of microbiology, immunology, infectious diseases, pathology, and pediatrics. Most are from U.S. hospitals and universities, including USC, Northwestern, and Univ of Chicago.

Table of Contents
1 Introduction to Infectious Diseases 1
2 Normal Flora in Health and Disease 5
3 The Immune System and Microbe-Induced Autoreactive Host Responses and Autoimmune Disease 15
4 Bacteria - Host Interactions 29
5 Virus-Host Interactions 47
6 Temperature Regulation, the Pathogenesis of Fever, and the Approach to the Febrile Patient 64
7 Bacterial Infections of the Upper Respiratory Tract 74
8 Viral Infections of the Upper Respiratory Tract, Infectious Mononucleosis, and the Chronic Fatigue Syndrome 98
9 Dental Infections and Other Diseases of the Oral Cavity 110
10 Infections of the Lower Respiratory Tract: General Considerations 123
11 Community-Acquired Bacterial Pneumonia 130
12 Viral Infections of the Lower Respiratory Tract 143
13 Mycobacterial Infections 157
14 Fungal Infections 176
15 Urinary Tract Infections: Cystitis and Pyelonephritis 192
16 Sexually Transmitted Diseases 208
17 Infectious Diarrhea 235
18 Common Intestinal Parasitic Infections 263
19 Viral Hepatitis 281
20 Introduction to Infections of the Central Nervous System 297
21 Common Etiologic Agents of Bacterial Meningitis 310
22 Viral Infections of the Central Nervous System 327
23 Human Immunodeficiency Virus Infection and AIDS 344
24 Diagnosis and Management of Infection in the Immunocompromised Host 361
25 Nosocomial Infections 382
26 Infections at the Extremes of Life 396
27 Infections Caused by Anaerobic Bacteria 408
28 Rickettsial Diseases 430
29 Zoonoses 443
30 Malaria 454
31 Exanthematous Diseases 467
32 Sepsis 475
33 Infective Endocarditis 490
34 Staphylococci, Staphylococcal Disease, and Toxic Shock Syndrome 505
35 Bone and Joint Infections: Septic Arthritis and Osteomyelitis 515
36 Laboratory Evaluation of Infectious Diseases 527
37 Mechanisms of Microbial Susceptibility and Resistance to Antimicrobial Agents 548
38 Antimicrobial Therapy 569
39 Antimicrobial Agent Susceptibility Testing and Monitoring of Drug Therapy 594
40 Principles of Immunization 604
Index 617

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