Acute Renal Failure a Companion to Brenner and Rector's the Kidney

Author: Bruce Molitoris
Published: August 2001
Publisher: W.B.S
ISBN: 0721691749
Hardcover Book
Number of Pages: 512

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The most common reason for a renal consult in a hospitalized patient is acute renal failure (ARF). This new companion book to Brenner and Rector's The Kidney provides the reader with the complete information necessary to understand, diagnose, and treat this serious and challenging condition. The first part of the book describes recent progress in the understanding of the pathophysiology of ARF, explaining the tremendous strides in the molecular and cellular aspects of cell injury and recovery. The remainder (and majority) of the text emphasizes the clinical spectrum and management of the different disease processes causing ARF. In these chapters, ARF is discussed in terms of its many associated disease processes such as pigment nephropathy, burns, infectious disease, and gastrointestinal and liver disease. This format allows for rapid referral and an in-depth understanding of all clinical aspects of ARF, including its most important aspect of management - to prevent the disease from becoming chronic, ultimately leading to dialysis and then transplantation.

Table of Contents:

Sect. I The Pathophysiology of Acute Renal Failure 1
Ch. 1 The Morphologic Basis of Acute Renal Failure 1
Ch. 2 Vascular Alterations in Acute Renal Failure: Roles in Initiation and Maintenance 13
Ch. 3 Terminal Pathways to Cell Death 30
Ch. 4 Oxidant Mechanisms in Acute Renal Failure 60
Ch. 5 Heme Oxygenase and Acute Renal Injury 78
Ch. 6 Inflammatory Response and Its Consequences in Acute Renal Failure 89
Ch. 7 Growth Factors, Signaling, and Renal Injury and Repair 101
Ch. 8 Cytoskeletal Alterations as a Basis of Cellular Injury in Acute Renal Failure 119
Ch. 9 Tight Junction and Adherens Junction Dysfunction During Ischemic Injury 132
Ch. 10 Heat Shock Proteins: Role in Prevention and Recovery From Acute Renal Failure 143
Sect. II The Clinical Spectrum of Acute Renal Failure 157
Ch. 11 Clinical and Laboratory Diagnosis of Acute Renal Failure 157
Ch. 12 Metabolic and Electrolyte Disturbances: Secondary Manifestations 169
Ch. 13 Imaging Techniques in Acute Renal Failure 192
Ch. 14 Hemoglobinuria 214
Ch. 15 Nontraumatic Rhabdomyolysis 220
Ch. 16 Post-Traumatic Acute Renal Failure With Emphasis on the Muscle Crush Syndrome 227
Ch. 17 Renal Failure in Disasters 236
Ch. 18 Acute Renal Failure in Burns 247
Ch. 19 Acute Renal Failure With Cardiovascular Disease 255
Ch. 20 Acute Renal Failure in Liver Disease 265
Ch. 21 Acute Renal Failure in Vasculitis 275
Ch. 22 Acute Renal Failure as a Result of Infectious Diseases 292
Ch. 23 Acute Renal Failure in Pregnancy 304
Ch. 24 Acute Renal Failure as a Result of Malignancy 312
Ch. 25 Acute Renal Failure in Solid-Organ Transplantation 322
Ch. 26 Acute Renal Failure After Bone Marrow Transplantation 349
Ch. 27 Nephrotoxicity From Antibacterial, Antifungal, and Antiviral Drugs 349
Ch. 28 Acute Renal Failure Associated With Cancer Chemotherapy 365
Ch. 29 Acute Renal Failure Associated With Radiocontrast Agents 376
Ch. 30 Biological Nephrotoxins 383
Ch. 31 Osmotic Nephropathy 391
Ch. 32 Acute Renal Failure Associated With Recreational Drug Use 397
Ch. 33 Acute Renal Failure and Nonsteroidal Anti-Inflammatory Drugs 406
Ch. 34 Acute Renal Failure Associated With Occupational and Environmental Settings 414
Sect. III Management of Acute Renal Failure 425
Ch. 35 Recovery From Acute Renal Failure 425
Ch. 36 Inflammatory Cells in Renal Damage and Regeneration 451
Ch. 37 Nutritional Support in Patients With Acute Renal Failure 465
Ch. 38 Multiple Organ System Failure 490
Ch. 39 Dialysis: Continuous Versus Intermittent Renal Replacement Therapy in the Treatment of Acute Renal Failure 497
Ch. 40 Predictive Factors and Scoring 507
Index 519

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