Cytokine Therapeutics in Infectious Diseases

Author: Steven M. Holland
Published: October 2001
Publisher: Lippincott Williams & Wilkins
ISBN: 078171625X
Hardcover Book
Number of Pages: 304

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Specialists in infectious disease introduce practitioners and students to cytokines and chemokines that are now being or close to being in use to enhance natural host defenses against infections. They also describe using anti-cytokines to dampen uncontrolled responses of the innate and adaptive immune systems. Among the topics they take up are the role of Interleukin-1 in sepsis, a series of other Interleukin numbers, chemokines in infectious diseases, the interferons, myeloid growth factor in supportive care of cancer and marrow transplant therapies, cytokine signal transduction, and cytokine-induced neuropsychiatric toxicity.

Table of Contents:

Contributing Authors
Foreword
Preface
Acknowledgments
1 The Role of Interleukin-1 in Sepsis 1
2 Interleukin-2 15
3 Interleukin-5 45
4 Interleukin-10 65
5 Interleukin-12 85
6 Interleukin-17 105
7 Interleukin-18 119
8 Chemokines in Infectious Disease 145
9 G-CSF and GM-CSF 185
10 The Interferons 221
11 Myeloid Growth Factors in Supportive Care of Cancer and Marrow Transplant Therapies 251
12 Cytokine Signal Transduction 295
13 Cytokine-Induced Neuropsychiatric Toxicity 323
Subject Index 333

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