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Table of Contents:

Contributing Authors
Preface
Acknowledgments
Pt. 1 Fundamentals of Hematology: Tools of the Trade
1 Consultation in Hematology 1
2 Laboratory Hematology: Methods for the Analysis of Blood 15
3 Examination of the Bone Marrow 59
4 Molecular Genetics and Genomics for the Hematologist 81
5 Cytogenetics for the Hematologist 95
6 Molecular Basis of Oncology 123
Pt. 2 Hematopoietic System
7 Hematopoiesis 147
Pt. 3 Stem Cell Disorders
8 Inherited Bone Marrow Failure Syndromes 209
9 Acquired Bone Marrow Failure Syndromes 273
10 Paroxysmal Nocturnal Hemoglobinuria 319
11 Myelodysplastic Syndromes 335
12 Myeloproliferative Disorders 379
13 Chronic Myelogenous Leukemia 433
Pt. 4 White Blood Cells
14 Neutrophils and Monocytes: Normal Physiology and Disorders of Neutrophil and Monocyte Production 455
15 Acute Myelogenous Leukemia 483
16 Structure, Function, and Functional Disorders of the Phagocyte System 531
17 Eosinophils, Basophils, and Mast Cells 569
18 Cellular and Molecular Biology of Lymphoid Cells 589
19 The Human Major Histocompatibility System 621
20 Reactive Lymphocyte Disorders and Lymphadenopathy 633
21 Disorders of the Spleen 649
22 Primary Immunodeficiency Diseases and Immunoproteins 673
23 Acquired Immunodeficiency Syndrome 713
24 Biology and Classification of Lymphoid Neoplasms 733
25 Acute Lymphoblastic Leukemia 779
26 Chronic Lymphoid Leukemias 805
27 Hodgkin's Disease 837
28 Non-Hodgkin's Lymphomas 861
29 Plasma Cell Tumors 889
30 Histiocytoses and Disorders of the Reticuloendothelial System 921
Pt. 5 Hemostasis
31 Hemostatic System 959
32 Platelet Life Cycle: Quantitative Disorders 983
33 Life of the Blood Platelet 1049
34 Platelet Membrane Proteins and Their Disorders 1081
35 Von Willebrand's Disease 1103
36 Contact System and Its Disorders 1131
37 Vitamin K-Dependent Blood Coagulation Proteins: Normal Function and Clinical Disorders 1157
38 Coagulation Factors V and VIII: Normal Function and Clinical Disorders 1195
39 Biology and Disorders of Fibrinogen and Factor XIII 1225
40 Fibrinolytic System and Its Disorders 1249
41 Disseminated Intravascular Coagulation 1275
42 Natural Anticoagulants and the Prethrombotic State 1303
43 Anticoagulant Therapy 1327
Pt. 6 Red Blood Cells
44 Introduction to Anemias 1345
45 Disorders of Cobalamin and Folate Metabolism 1361
46 Disorders of Iron Metabolism 1399
47 Disorders of Heme Production and Catabolism 1435
48 Hemoglobin Synthesis and the Thalassemias 1503
49 Disorders of Hemoglobin Function and Stability 1597
50 Sickle Syndromes 1655
51 Disorders of the Red Blood Cell Membrane 1709
52 Autoimmune Hemolytic Anemia 1859
53 Disorders of Erythrocyte Glycolysis and Nucleotide Metabolism 1887
54 Glucose-6-Phosphate Dehydrogenase Deficiency and Related Disorders 1921
55 Neonatal Anemia 1951
Pt. 7 Systemic Disease
56 Hematologic Aspects of Systemic Diseases 1977
Pt. 8 Hematologic Therapies
57 Transfusion Medicine 2011
58 Hematologic Growth Factors as Supportive Care 2069
59 Clinical Pharmacology of Anticancer Drug 2095
60 Hematopoietic Stem Cell Transplantation 2133
App Data of Importance in Hematology 2191
Index 2233