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Table of Contents:

Preface
Contributing Authors
Sect. I Biochemical, Structural, and Functional Correlations in the Kidney
1 Structural-Functional Relationships in the Kidney 3
2 Renal Circulation and Glomerular Hemodynamics 59
3 Regulation of Water Balance: Urine Concentration and Dilution 109
4 Tubular Sodium Transport 135
5 Tubular Potassium Transport 177
6 Renal Acid-Base Transport 203
7 Renal Metabolism 217
8 Renal Transport of Organic Ions and Uric Acid 243
9 Hormones and the Kidney 265
Sect. II Clinical Evaluation
10 Urinalysis 317
11 Laboratory Evaluation of Renal Function 333
12 Intravenous Urography, Ultrasonography, and Radionuclide Studies 371
13 Computed Tomography and Magnetic Resonance Imaging 411
14 Diagnostic and Therapeutic Angiography of the Renal Circulation 431
15 Indications for and Interpretation of the Renal Biopsy: Evaluation by Light, Electron, and Immunofluorescence Microscopy 457
Sect. III Hereditary Diseases
16 Introduction to Genetic Renal Disease 491
17 Nephronophthisis, Medullary Cystic and Medullary Sponge Kidney Disease 521
18 Polycystic Kidney Disease 547
19 Alport's Syndrome, Fabry's Disease, and Nail-Patella Syndrome 589
20 Isolated Renal Tubular Disorders: Molecular Mechanism and Clinical Expression of Disease 621
Sect. IV Urological Diseases of the Genitourinary Tract
21 Congenital Urologic Anomalies 649
22 Disorders of Micturition 663
23 Prostatitis, Orchitis, and Epididymitis 695
24 Vesicoureteric Reflux and Reflux Nephropathy 713
25 Urinary Tract Obstruction 757
26 Nephrolithiasis 789
Sect. V Neoplasms of the Genitourinary Tract
27 Molecular Mechanisms of Renal Cancer 819
28 Primary Neoplasms of the Kidney and Renal Pelvis 831
29 Bladder Cancer 851
30 Prostatic Carcinoma 869
31 Testicular Carcinoma 889
Sect. VI Infections of the Urinary Tract and the Kidney
32 Host-Parasite Interactions and Host Defense Mechanisms 903
33 Cystitis and Urethritis 923
34 Infections of the Upper Urinary Tract 941
35 Renal and Perirenal Abscesses 971
36 Complicated Urinary Tract Infections 985
37 Fungal Urinary Tract Infections 999
38 Urinary Tract Tuberculosis 1017
Sect. VII Acute Renal Failure
39 Pathophysiology of Ischemic Acute Renal Injury 1041
40 Pathophysiology of Nephrotoxic Cell Injury 1071
41 Acute Renal Failure 1093
42 Antibiotic- and Immunosuppression-Related Renal Failure 1137
43 Renal Diseases Induced by Antineoplastic Agents 1175
44 Nephrotoxicity of Nonsteroidal Antiinflammatory Agents, Analgesics, and Angiotensin-Converting Enzyme Inhibitors 1189
45 Radiocontrast Media-Induced Acute Renal Failure 1211
46 Nephrotoxicity Secondary to Drug Abuse and Lithium Use 1225
47 Nephrotoxicity Secondary to Environmental Agents and Heavy Metals 1255
48 Acute Tubulointerstitial Nephritis 1273
49 Acute Renal Failure Associated with Pigmenturia or Crystal Deposits 1299
Sect. VIII Hypertension
50 Blood Pressure and the Kidney 1329
51 Hypertension Associated with Renal Parenchymal Disease 1363
52 Renal Artery Stenosis, Renal Vascular Hypertension, and Ischemic Nephropathy 1399
53 Hypertension and Pregnancy 1459
54 Pathogenesis and Treatment of Hypertension in the Diabetic Patient 1489
55 Hypertension Associated with Endocrine Disorders 1501
56 Malignant Hypertension and Other Hypertensive Crises 1513
Sect. IX Glomerular, Interstitial, and Vascular Renal Diseases
57 Mechanisms of Tissue Injury and Repair 1595
58 Acute Poststreptococcal Glomerulonephritis and Other Bacterial Infection-Related Glomerulonephritis 1617
59 Viral Glomerular Diseases 1633
60 Rapidly Progressive Glomerulonephritis 1665
61 Immunoglobulin A Nephropathy and Henoch-Schonlein Purpura 1691
62 Membranoproliferative Glomerulonephritis 1717
63 Membranous Nephropathy 1743
64 Nephrotic Syndrome: Minimal Change Disease, Focal Glomerulosclerosis, and Related Disorders 1773
65 Renal Involvement in Systemic Lupus Erythematosus 1833
66 Renal Disorders Associated With Systemic Sclerosis, Rheumatoid Arthritis, Sjogren's Syndrome, and Polymyositis-Dermatomyositis 1861
67 Thrombotic Thrombocytopenic Purpura, Hemolytic-Uremic Syndrome, and Acute Cortical Necrosis 1883
68 Vasculitic Diseases of the Kidney 1911
69 Mixed Cryoglobulinemia 1939
70 Renal Artery Thrombosis, Thromboembolism, Aneurysms, Atheroemboli, and Renal Vein Thrombosis 1951
71 The Long-Term Outcome of Glomerular Diseases 1981
72 Chronic Tubulointerstitial Nephropathies 2045
Sect. X Systemic Diseases of the Kidney
73 Diabetic Nephropathy 2083
74 The Normal and Diseased Kidney in Pregnancy 2129
75 Liver Disease and the Kidney 2167
76 Monoclonal Gammopathies: Multiple Myeloma, Amyloidosis, and Related Disorders 2205
77 Hyperuricemia, Gout, and the Kidney 2255
78 Sickle Cell Disease 2281
79 Tropical Nephrology 2301
80 Kidney Disease in Children 2351
81 Renal Function and Disease in the Aging Kidney 2387
Sect. XI Disorders of Electrolyte, Water, and Acid-Base
82 Mechanisms of Diuretic Action 2423
83 Idiopathic Edema 2455
84 Cardiac Failure, Liver Disease, and the Nephrotic Syndrome 2465
85 The Syndrome of Inappropriate Antidiuretic Hormone Secretion and Other Hypoosmolar Disorders 2511
86 Nephrogenic and Central Diabetes Insipidus 2549
87 Disorders of Potassium and Acid-Base Metabolism in Association with Renal Disease 2577
88 Disorders of Phosphorus, Calcium, and Magnesium Metabolism 2607
89 Fluid-Electrolyte and Acid-Base Disorders Complicating Diabetes Mellitus 2661
Sect. XII Uremic Syndrome
90 Pathophysiology and Nephron Adaptation in Chronic Renal Failure 2689
91 Anemia in Renal Disease 2719
92 The Osteodystrophy of Chronic Renal Failure 2735
93 Nervous System Manifestations of Renal Failure 2769
94 Cardiac Disease in Chronic Renal Disease 2795
95 Metabolic and Endocrine Dysfunctions in Uremia 2815
Sect. XIII Management of End-Stage Renal Disease
96 Immunobiology and Immunopharmacology of Graft Rejection 2857
97 Outcomes and Complications of Renal Transplantation 2871
98 Peritoneal Dialysis 2939
99 Center and Home Chronic Hemodialysis: Outcome and Complications 2979
100 Ethical and Legal Considerations in End-State Renal Disease 3007
Sect. XIV Nutrition, Drugs, and the Kidney
101 Protein Intake and Prevention of Chronic Renal Disease 3047
102 Phosphate, Aluminum, and Other Elements in Chronic Renal Failure 3071
103 Dietary Considerations in Patients with Chronic Renal Failure, Acute Renal Failure, and Transplantation 3085
104 Use of Drugs in Patients with Renal Failure 3139
Subject Index