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Preface
List of Contributors
Mechanisms of Substance P-Mediated Nociception and Opioid-Mediated Antinociception 1
Spinal Cord Neuronal Plasticity: Mechanisms of Persistent Pain Following Tissue Damage and Nerve Injury 19
Local Anesthetic Pharmacology 35
Pain Research and Basic Science: Pain and the Sympathetic Nervous System 65
Local Anesthesia Toxicity 77
Effect of Postoperative Pain on Surgical Stress Response 99
Postoperative Pain Assessment and Choice of Methods of Treatment 105
Patient-Controlled Analgesia (Part I): Historical Perspective 117
Problems in the Management of Postoperative Pain 127
Patient-Controlled Analgesia (Part II): An Update On Clinical Usage 133
Organization and Operation of an Acute Pain Service 143
Role of Non-Opioid Analgesics in the Peri-Operative Period 151
Effect of Postoperative Pain on Surgical Outcome 171
Postoperative Pain Management in Children 177
Preemptive Analgesia 189
The Spinal Route Of Analgesia: Opioids and Future Options 195
Problems of Pain Measurement in Children 227
Post Spinal Cord Injury Pain: Mechanisms and Treatment Options 237
Prevention of Post-Herpetic Neuralgia 253
Opioids in the Management of Non-Malignant Chronic Pain 265
Epidural Steroids 273
Multidisciplinary Evaluation and Management of Chronic Pain 281
Cancer Pain Syndromes 287
Managing the Unmanageable 305
Issues in Opioid Therapy for the Treatment of Cancer Pain 311
Neurolytic Blocks - Current Status in the Treatment of Cancer and Chronic Pain 333
Chronic Pain Management in Children 343
Alternative Drug Delivery Systems 351
Physician Assisted Suicide and Euthanasia 373
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