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Cardiac Metabolism in Health and Disease

Author: Salah Abdel-Aleem
Published: January 1998
Publisher: Kluwer Academic Publishers
ISBN: 0792381041
Hardcover Book
Number of Pages: 202
 
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Cardiac Metabolism in Health and Disease


Table of Contents:


Preface 1
Glucose and glycogen utilisation in myocardial ischemia - Changes in metabolism and consequences for the myocyte 3
Differential regulation in the heart of mitochondrial carnitine palmitoyltransferase-I muscle and liver isoforms 27
Carnitine deficiency-induced cardiomyopathy 33
Fatty acid-binding proteins in the heart 43
Metabolic disturbances in diabetic cardiomyopathy 53
Diabetes mellitus and cardiac function 59
Phospholipase A[subscript 2]-mediated hydrolysis of cardiac phospholipids: The use of molecular and transgenic techniques 65
The role of glucose metabolism in a pig heart model of short-term hibernation 75
Glucose metabolism, H[superscript +] production and Na[superscript +]/H[superscript +]-exchanger mRNA levels in ischemic hearts from diabetic rats 85
Regulation of carbohydrate and fatty acid utilization by L-carnitine during cardiac development and hypoxia 95
Identification of nucleoside transport binding sites in the human myocardium 105
Mutagenesis and characterization of specific residues in fatty acid ethyl ester synthase: A gene for alcohol-induced cardiomyopathy 111
Palmitate oxidation by the mitochondria from volume-overloaded rat hearts 117
Effects of phosphodiesterase inhibitors on glucose utilization in isolated cardiac myocytes 129
Energy metabolism and mechanical recovery after cardioplegia in moderately hypertrophied rats 137
Role of nucleoside transport and purine release in a rabbit model of myocardial stunning 145
Ischemic preconditioning in rat heart: No correlation between glycogen content and return of function 153
The liver isoform of carnitine palmitoyltransferase I is activated in neonatal rat cardiac myocytes by hypoxia 163
Human myocardial ATP content and in vivo contractile function 171
Differential cardioprotection with selective inhibitors of adenosine metabolism and transport: Role of purine release in ischemic and reperfusion injury 179
Effects of nucleoside transport inhibitors and adenine/ribose supply on ATP concentration and adenosine production in cardiac myocytes 193
Index to Volume 180 201


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Cardiac Metabolism in Health and Disease





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