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Table of Contents:

List of Contributors
Preface
I Adenosine
1 Molecular Biology and Pharmacology of Recombinant Human Adenosine Receptors 1
2 Cardiac Physiology of Adenosine 21
3 Vascular Biology and Pharmacology of Adenosine Receptors 40
4 Roles of Adenosine in Angiogenesis 49
5 Adenosine, K[subscript ATP] Channel and Cardioprotection in the Intact Heart 64
6 Adenosine Receptor Subtypes and Cardioprotection in Cardiac Myocyte and Transgenic Models 86
7 Regulation of Adenosine Receptor Sybtypes and Cardiac Dysfunction in Human Heart Failure 108
8 Adenosine and Cardiac Arrhythmias 126
9 Adenosine and Cardiac Aging 143
II Nucleotides
10 Molecular Biology of P2X Purinoceptors 159
11 The G Protein-Coupled P2Y Receptors 187
12 P2 Purinoceptors in Blood Vessels 206
13 P2 Purinoceptors and Cardiac Functions 225
14 Vascular P2 Receptors and Their Possible Role in Hypertension 243
III Interaction Between P1 and P2 Receptors
15 Neuromodulation in the Cardiovascular System 257
16 Adenosine Receptors, Blood Vessel and Inflammation 271
17 P2 Purinoceptors and Regulation of the Function of Platelets, Erythrocytes and Mast Cells 290
18 Purinoreceptors and T Cell Function: Regulation of Lymphocyte Activation by Extracellular ATP and Adenosine 302
19 Recent Advances in Cardiac Adenosine Metabolism 312
20 The Role of Peripheral Autonomic Neurons with P[subscript 1]-and/or P[subscript 2] Purinoreceptors in Cardiac Regulation 326
21 Extracellular Metabolism of Nucleotides and Adenosine in the Cardiovascular System 342
Index 359