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Series Editor's Foreword
Preface
List of Contributors
1 The role of T cells in the immunopathogenesis of the connective tissue diseases: rheumatoid arthritis as the paradigm 1
2 B cells and rheumatoid factors in rheumatoid arthritis 23
3 The mononuclear phagocyte and rheumatoid arthritis 43
4 The HLA association with rheumatoid arthritis 75
5 Cytokines and inflammatory arthritis 83
6 Adhesion molecules involved in leukocyte endothelial cell interactions 95
7 The complement system and connective tissue disease 119
8 The acute phase response 147
9 Animal models of systemic lupus erythematosus 157
10 Animal models of arthritis 193
11 Lyme arthritis: pathogenetic principles emerging from studies in man and mouse 205
12 Retroviral arthritis in animals and man 231
13 Autoantibodies against DNA 257
14 Immunology of antiphospholipid antibodies 279
15 Autoantigens in connective tissue diseases 305
16 Sjogren's syndrome: from polyclonal B cell activation to monoclonal B cell proliferation 335
17 Immunotherapy 355
18 Immune reactivity against heat shock proteins and arthritis 383
Index 399