Immunology and Serology in Laboratory Medicine

Author: Mary Louise Turgeon
Published: December 1995
Publisher: Mosby, Incorporated
ISBN: 0815187874
Hardcover Book
Number of Pages: 496

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Covering theory, practice, and clinical applications of immunology and serology, this textbook is suited for clinical laboratory science and technical students. It describes basic immunological mechanisms, clinical procedures, the features of infectious diseases and autoimmune disorders, and transplantation and tumor immunology. Case studies ground the discussion. Turgeon teaches medical laboratory science at Tufts University. This second edition covering clinical immunology and serology provides good introductions to methodologies, clinical applications, and interpretations for all areas of clinical immunology. According to the author, the purpose of the second edition of the book is to describe the basic theoretical concepts; ... theory of procedures; ... disorders; and ... applicable procedures for specific disorders. An updated clinical immunology student text is always a welcome addition in this changing field and is a worthy objective. For the most part, the objectives of the author have been met. This book is written for beginning students in immunology, who need an emphasis on the medical aspects of the discipline and the practical aspects of serology. The book is well written with a student in mind and could also serve as a source for immunology review for a medical technician or medical technologist. The author appears to be a credible educator whose previous book has been used as a text for our medical technology students. The book contains many useful black-and-white illustrations; however, the print quality of the illustrations is poor and they do not look professionally drawn. There are many good black-and-white pictures. There are no color plates illustrating white cell morphology or indirect immunofluorescent testing for autoantibodies such as antinuclear antibodies, which would have added a great deal. The references are pertinent and up-to-date. The table of contents is adequate. The index is quite good and there is a very useful glossary in the back. The The appendixes are also quite helpful. This book contains a great deal of good information and explanation of clinicalimmunology. The safety section is weak, failing to mention the potential for hepatitis C infection from blood and fluids. Subjective opinions that may not be shared by other professionals in the immunology field can be found. Overall, this book will be very useful as a text for clinical laboratory students and as a resource for review of clinical immunology field for medical technicians and technologists. Libraries at undergraduate and graduate schools that have a clinical laboratory program should carry this book. Medical school and hospital libraries should carry this book as well.

Table of Contents
Pt. 1 Basic Immunologic Mechanisms 1
1 An Overview of Immunology 3
2 Antigens and Antibodies 15
3 The Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells 37
4 The Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells 55
5 Soluble Mediators of the Immune Systems 87
Pt. 2 The Theory of Immunologic and Serologic Procedures 115
6 Safety and Basic Techniques in the Immunology-Serology Laboratory 117
7 Agglutination Methods 131
8 Electrophoresis Techniques 141
9 Labeling Techniques in Immunoassay 149
10 Automated Procedures 157
11 Molecular Techniques 165
12 Miscellaneous Techniques 175
Pt. 3 Immunologic Manifestations of Infectious Diseases 185
13 The Immune Response in Infectious Diseases 187
14 Streptococcal Infections 195
15 Syphilis 207
16 Tick-Borne Diseases 227
17 Toxoplasmosis 247
18 Cytomegalovirus 255
19 Infectious Mononucleosis 271
20 Viral Hepatitis 283
21 Rubella Infection 311
22 Acquired Immunodeficiency Syndrome (AIDS) 325
Pt. 4 Immunologically and Serologically Related Disorders 345
23 Hypersensitivity Reactions 347
24 Immunoproliferative Disorders 359
25 Autoimmune Disorders 373
26 Systemic Lupus Erythematosus 401
27 Rheumatoid Arthritis 421
28 Solid Organ Transplantation 437
29 Bone Marrow Transplantation 459
30 Tumor Immunology 473
Answers to Review Questions 491
App. A Preparing Dilutions and Serial Dilutions 495
App. B Review Questions 497
App. C Chronic Fatigue Syndrome 501
App. D A Primer on Vaccines 507
App. E Apoptosis 511
App. F Diagnostic Tests in Medical Laboratory Immunology 513
Glossary 521

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