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Cardiovascular Drug Development: Protocol Design and Methodology, Vol. 35

Author: Jeffrey S. Borer
Published: November 1998
Publisher: Marcel Dekker
ISBN: 0824719271
Hardcover Book
Number of Pages: 232
 
Click to compare book prices for Cardiovascular Drug Development: Protocol Design and Methodology, Vol. 35
Cardiovascular Drug Development: Protocol Design and Methodology, Vol. 35


Table of Contents:


Series Introduction
Preface
Contributors
Drug Discovery and Development 1
Background Therapy in Congestive Heart Failure Studies 49
Congestive Heart Failure Trial Design 57
Angiotensin Converting Enzyme Inhibitors for Mortality Reduction in Congestive Heart Failure: Should Approval Be Granted for a Class Effect? 63
Sudden Death in Congestive Heart Failure Trials 71
Panel Discussion 75
Antihypertensive Clinical Trials 101
Calcium Channel Blockers: Safety Issues 107
Panel Discussion 121
Antiarrhythmics: Indications, Claims, and Trial Design 137
Supraventricular Tachycardia Drugs and Trial Design Issues 141
Antiarrhythmic Trials: Update 145
Inter-Ethnic Differences in the Susceptibility to Drug-Induced QT Interval Prolongation and Torsade de Pointes 151
Panel Discussion 159
Antilipid Trial Endpoints 177
Natural History Endpoints and Angina Trials 185
Development of Antiplatelet Drugs 189
Panel Discussion 197
Future Directions of Cardiovascular Drug Development 213
Index 223


Click to compare book prices for Cardiovascular Drug Development: Protocol Design and Methodology, Vol. 35
Cardiovascular Drug Development: Protocol Design and Methodology, Vol. 35





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