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Series Introduction
Foreword
Preface
Contributors
1 Unique Aspects of Infection in Older Adults 1
2 Age-Related Changes in Host Defenses 9
3 Clinical Approach to Diagnosis of Infections in Older Patients 23
4 Pharmacology of Antimicrobial Agents with Aging 33
5 Assay Methods for Antimicrobial Therapy 47
6 Drug Prescribing, Compliance, and Adverse Reactions 55
7 Penicillins 69
8 Cephalosporins 99
9 Monobactams 125
10 Carbapenems 135
11 Beta-Lactamase Inhibitors 151
12 Trimethoprim-Sulfamethoxazole 169
13 Aminoglycosides 183
14 Quinolones 237
15 Vancomycin 311
16 Tetracylines 323
17 Erythromycin and Newer Macrolides 333
18 Clindamycin 353
19 Metronidazole 367
20 Chloramphenicol 379
21 Nitrofurans 391
22 Methenamine 403
23 Antituberculosis Agents 411
24 Antifungal Agents 441
25 Antiviral Therapy 457
26 Empiric Antimicrobial Therapy 469
27 Antimicrobial Therapy in the Ambulatory Setting 479
28 The Use of Antimicrobials in Nursing Homes 485
29 Home Intravenous Antibiotic Therapy 505
30 Antimicrobial Prophylaxis 521
31 Immunoprophylaxis 539
Index 551