Handbook of Olfaction and Gustation, Vol. 32

Author: Richard L. Doty
Published: January 1995
Publisher: Marcel Dekker
ISBN: 0824792521
Hardcover Book
Number of Pages: 881

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The book contains predominantly black-and-white illustrations, with some color illustrations. Both main sections—olfaction and gustation—are thricely subdivided into the topics of anatomy and neurobiology; functional measurement, ontogeny, and genetics; and clinical applications and perspectives. The last and much shorter section on other chemosensory systems is all-of-a-piece. The new edition contains an author index and 10 new chapters to account for growth in such fields as neuroscience, functional imaging, cybernetics, toxicology, structure-activity assessment, molecular biology, and animal behavior. The Handbook is meant to appeal to a wide range of medical specialists and basic scientists in academia, industry, and government, and can serve as a textbook for graduate, medical, and postdoctoral fellows from an array of disciplines. Most contributors are from the US. This new book in the series ""Neurological Disease and Therapy"" addresses gustation and olfaction, incorporating the contributions of experts in different areas from otorhinolaryngology to virology. Most of them work in the United States. The purpose is to present a synthesis of a large body of basic and clinical knowledge on the senses of smell and taste, dividing each sense in three clear sections that focus on basic anatomo-physiology, psychophysics, and neurophysiology, and in clinical applications. Thus, this book provides a needed reference book, largely meeting the editor's objective. The present book is basically oriented to neuroscientists, but it is also useful for neurologists and other clinicians in this field. The authors and contributors are in general known and credible authorities in their respective areas. This book includes many photographs, figures, charts, and tables that ease the understanding of the text. The references are voluminous and adequate giving an up-to-date, as well as an historical perspective. The table of contents is especially useful to navigate through this text printed in a high quality paper. This is an interesting book that offers strong basic scientific knowledge, along with clinical applications in olfaction and gustation fields, gathering material in one place that is not available in such a compiled way elsewhere. It will become a basic reference book for neuroscientists and clinicians interested in the senses of smell and taste. Doty, Richard L., PhD (Univ of Pennsylvania)The contributors represent the specialties of otorhinolarygology, neuroscience, physiology, biophysics, psychology, pharmacology, toxicology, and anatomy. Most are from hospitals and universities in the U.S., with others from France, Germany, Australia, and the U.K. Institutions prominently represented include Univ of Pennsylvania Medical Center, Oxford, Johns Hopkins, Rockefeller Univ, Yale, and Northwestern.

Table of Contents
Foreword
Preface
Contributors
Introduction and Historical Perspective
I Olfaction
A Anatomy and Neurobiology
1 Anatomy of the Human Nasal Passages 1
2 Morphology of the Mammalian Olfactory Epithelium: Form, Fine Structure, Function, and Pathology 17
3 Olfactory Mucosa: Composition, Enzymatic Localization, and Metabolism 51
4 Molecular Neurobiology of Olfactory Transduction 75
5 Neurogenesis in the Adult Olfactory Neuroepithelium 93
6 Developmental Anatomy of the Olfactory System 115
7 Anatomy and Neurochemistry of the Olfactory Bulb 139
8 Central Olfactory Structures 165
9 Sensory Physiology of Central Olfactory Pathways 181
B Functional Measurement, Ontogeny, and Genetics
10 Psychophysical Measurement of Human Olfactory Function, Including Odorant Mixture Assessment 203
11 Electrophysiological Measurement of Olfactory Function 229
12 Functional Neuroimaging of Human Olfaction 251
13 Structure-Odor Relationships: A Modern Perspective 275
14 Olfactory System Cybernetics: Artificial Noses 295
15 Olfaction and the Development of Social Behavior in Neonatal Mammals 309
16 Genetics of Olfactory Perception 329
17 Mammalian Pheromones: Fact or Fantasy? 345
18 Psychophysical Evaluation of Olfaction in Nonhuman Mammals 385
19 Methods for Determining Odor Preferences in Nonhuman Mammals 403
20 Olfactory Memory 409
C Clinical Applications and Perspectives
21 Nasal Patency and the Aerodynamics of Nasal Airflow: Measurement by Rhinomanometry and Acoustic Rhinometry, and the Influence of Pharmacological Agents 439
22 Clinical Disorders of Olfaction 461
23 Odor Perception in Neurodegenerative Diseases 479
24 Olfactory System Neuropathology in Alzheimer's Disease, Parkinson's Disease, and Schizophrenia 503
25 Multiple Chemical Intolerance 525
26 The Olfactory System and the Nasal Mucosa as Portals of Entry of Viruses, Drugs, and Other Exogenous Agents into the Brain 549
27 Influence of Environmental Toxicants on Olfactory Function 575
28 Evaluation of Olfactory Deficits by Structural Medical Imaging 593
29 Plasticity Within the Olfactory Pathways: Influences of Trauma, Deprivation, Stem Cells, and Other Factors 615
30 Head Injury and Olfaction 629
II Gustation
A Anatomy and Neurobiology
31 Saliva: Its Role in Taste Function 639
32 Morphology of the Peripheral Taste System 651
33 Central Taste Anatomy and Neurophysiology 679
34 Molecular Physiology of Gustatory Transduction 707
35 Gustatory Neural Coding 731
36 Development of the Taste System: Basic Neurobiology 759
B Functional Measurement, Ontogeny, and Genetics
37 Contemporary Measurement of Human Gustatory Function 783
38 Human Perception of Taste Mixtures 805
39 The Ontogeny of Human Flavor Perception 823
40 Genetics of Human Taste Perception 847
41 Psychophysical Evaluation of Taste Function in Nonhuman Mammals 861
C Clinical Applications and Perspectives
42 Nutritional Implications of Taste and Smell 881
43 Conditioned Taste Aversions 905
44 Clinical Disorders Affecting Taste: Evaluation and Management 935
45 Head Injury and Taste 959
III Other Chemosensory Systems
46 The Vomeronasal Organ 967
47 Trigeminal Chemosensation 981
48 The Structure and Function of the Nervus Terminalis 1001
Author Index 1027
Subject Index 1103

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