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Preface
Contributors
1 An Introduction to Primitive Hematopoietic Cells 1
2 Bone Marrow Stroma: Its Role in Hematopoiesis 29
3 Neutrophils and Macrophages 49
4 Migration, Function, and Activation of Myeloid Cells 89
5 Erythroid Cells 107
6 Bone Marrow Control of Megakaryocytopoiesis 129
7 The Role of Interleukin-5 in Eosinophilia and Allergy 161
8 Mast Cells and Basophils 189
9 Molecular Mechanisms of Signal Transduction in Hematopoietic Lineages 209
10 Regulation of Proliferation, Differentiation, and Apoptosis in Normal Lymphopoiesis and in Acute Lymphoblastic Leukemia 259
11 Therapeutic Modulation of Hematopoietic Cells in Myelodysplastic Syndromes by Hematopoietic Growth Factors 299
12 Malignant Transformation of Myeloid and Lymphoid Cells: Emphasis on Stem Cell Factor and Its Receptor c-kit 311
13 Therapeutic Modulation of Mature Cell Production 337
Index 369