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Table of Contents:

Contributors
Foreword
Preface
I Orientation 1
1 Introduction, History, Controversies, and Definitions 3
2 Epidemiology of Hypertension 43
II Cardiovascular Adaptation to Normal Pregnancy 67
3 Hemodynamic Changes 69
4 Control of Volume and Body Tonicity 103
III Clinical Spectrum of Preeclampsia 167
5 Preeclampsia-Eclampsia 169
6 Prediction and Differential Diagnosis 201
IV Pathology and Pathophysiology of Preeclampsia 229
7 Pathology of the Kidney, Liver, and Brain 231
8 Renal and Cardiovascular Alterations 263
9 Alterations in Volume Homeostasis 327
10 Platelet and Coagulation Abnormalities 349
V The Etiology of Preeclampsia 375
11 Defects in Placentation and Placental Perfusion 377
12 Endothelial Cell Dysfunction 395
13 Genetic Factors 431
14 Lipid Metabolism and Oxidative Stress 453
15 Animal Models 487
VI Prevention and Management of Preeclampsia 517
16 Prevention of Preeclampsia 519
17 Management of Preeclampsia 543
18 Antihypertensive Treatment 581
19 Chronic Hypertension and Pregnancy 605
Index 635