Physiological Basis of Aging and Geriatrics,Third Edition

Author: Paola S. Timiras
Published: September 2002
Publisher: CRC Press
ISBN: 0849309484
Hardcover Book
Number of Pages: 464

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Extensively revised and updated to reflect the current state of knowledge in the study of aging, the third edition of the bestselling Physiological Basis of Aging and Geriatrics provides an even more complete profile of the aging of individuals and populations. It includes aspects of demographic, comparative, and differential aging together with a discussion of the several theories of aging. It shows how body functions change with aging, describes how both genetic and environmental factors influence age-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Divided into three main sections, the book first provides a broad and solid background in basic processes of biogerontology. Then it presents a survey of the aging of body systems, focusing on maintenance of optimal function and ability to adapt to environmental demands. Finally, it provides a synopsis of pharmacologic, nutritional, and physical exercise guidelines for preserving physical and mental health into senescence. This book presents up-to-date information from internationally renowned experts in various biologic fields using physiology as the unifying concept. Illustrated with numerous tables and graphs, Physiological Basis of Aging and Geriatrics, Third Edition focuses on the established facts of physiological aging to provide an essential reference book for a wide spectrum of readers with different levels of biological and educational backgrounds.

Summarizes current knowledge on the physiologic, genetic, and molecular mechanisms that may contribute to the aging of humans. Most of the 24 chapters describe the normal aging changes that occur in a particular body system or organ. The third edition reflects recent therapeutic developments and recent advances in genetics and molecular biology.

Table of Contents:

Pt. I General Perspectives
Ch. 1 Aging as a Stage of Life, Common Terms Related to Aging, Methods Used to Study Aging 3
Ch. 2 Human Longevity in Historical Perspective 11
Ch. 3 Comparative and Differential Aging, Geriatric Functional Assessment, Aging and Disease 25
Ch. 4 Cellular Senescence and Cell Death 47
Ch. 5 Oxidants and Antioxidants in Aging 61
Ch. 6 Theories of Life Span and Aging 85
Pt. II Systemic and Organismic Aging
Ch. 7 The Nervous System: Structural and Biochemical Changes 99
Ch. 8 The Nervous System: Functional Changes 119
Ch. 9 Sensory Systems: Normal Aging, Disorders, and Treatments of Vision and Hearing in Humans 141
Ch. 10 The Adrenals and Pituitary 167
Ch. 11 The Female Reproductive System 189
Ch. 12 The Ensemble Male Hypothalamo-Pituitary-Gonadal Axis 213
Ch. 13 The Thyroid, Parathyroid, and Pineal Glands 233
Ch. 14 The Endocrine Pancreas, Diffuse Endocrine Glands and Chemical Mediators 251
Ch. 15 The Immune System 265
Ch. 16 Cardiovascular Alterations with Aging: Atherosclerosis and Coronary Heart Disease 285
Ch. 17 Lipids, Lipoproteins and Atherosclerosis 305
Ch. 18 The Pulmonary Respiration, Hematopoiesis and Erythrocytes 319
Ch. 19 The Kidney, the Lower Urinary Tract, Body Fluids and the Prostate 337
Ch. 20 The Gastrointestinal Tract and the Liver 359
Ch. 21 The Skeleton, Joints, and Skeletal and Cardiac Muscles 375
Ch. 22 The Skin 397
Pt. III Prevention and Rehabilitation
Ch. 23 Pharmacology and Drug Management in the Elderly 407
Ch. 24 Healthful Aging: Nutrition and Exercise and Experimental Strategies in Dietary Restriction 415
Index 443

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