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Table of Contents:

Sect. I Effect on the Female Reproductive System
1 Nontraditional Sites of Endocrine Disruption by Chemicals on the Hypothalamus-Pituitary-Gonadal Axis: Interactions with Steroid Membrane Receptors, Monoaminergic Pathways, and Signal Transduction Systems 3
2 Diethylstilbestrol (DES) and Environmental Estrogens Influence the Developing Female Reproductive System 39
3 Ovotoxic Environmental Chemicals: Indirect Endocrine Disruptors 57
4 Dietary Phytoestrogens 89
5 Estrogens, Xenoestrogens, and the Development of Neoplasms 125
6 Differential Regulation of Gene Expression by Estrogenic Ligands: A Potential Basis for the Toxicity of Environmental Estrogens 165
7 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and Related Environmental Antiestrogens: Characterization and Mechanism of Action 187
Sect. II Effect on the Male Reproductive System
8 Endocrine Disruptors and Male Infertility 225
9 Environmental Antiandrogens as Endocrine Disruptors 247
10 Endocrine Disruptors and Sexual Dysfunction 279
11 The Role of Natural and Manmade Estrogens in Prostate Development 307
12 Metal Ions and Prostate Cancer 329
Index 339