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Molecular Bases of Anesthesia

Author: Eric Moody
Published: December 2000
Publisher: CRC Press
ISBN: 0849385555
Hardcover Book
Number of Pages: 352
 
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Molecular Bases of Anesthesia


Molecular Bases of Anesthesia provides a clear overview of the state of knowledge about anesthetic mechanisms at the molecular level of occurrence and focusing on the latest state-of-the-art techniques that relate to how anesthetic drugs cause unconsciousness. With contributions by leading experts, this timely book includes chapters on how to evaluate theories of anesthesia in general and includes discussion of some of the techniques, such as genetics, that can be used to address problems. Also discussed are anesthetic actions at major brain targets with a special emphasis on ion channels and areas of controversy in the field. This reference provides a broad survey of anesthetic actions, including hyperbaric pressure and anesthesia; volatile anesthetic interactions with proteins; and structure activity relationships of volatile anesthetics. Molecular Bases of Anesthesia stands alone as an in-depth, authoritative guide.


Table of Contents:

INTRODUCTION

Phil Skolnick and Eric Moody

BASIC PHARMACOLOGY OF VOLATILE ANESTHETICS

James P. Dilger

EXPERIMENTAL APPROACHES TO THE STUDY OF VOLATILE ANESTHETIC-PROTEIN INTERACTIONS

Jonas S. Johannsson, Roderic G. Eckenhoff

PRESSURE AND ANESTHESIA

Stephen Daniels, D. Phil

GENETICS AND ANESTHETIC MECHANISMS

Philip G. Morgan, Margaret M. Sedensky

STRUCTURE-ACTIVITY RELATIONSHIPS OF INHALED ANESTHETICS

Donald D. Koblin

VOLATILE ANESTHETIC EFFECTS ON CALCIUM

CHANNELS

Hugh C. Hemmings, Jr.

INHALATION ANESTHETIC EFFECTS ON NEURONAL PLASMA MEMBRANE CA2+ -ATPASE

Piotr K. Janicki

ANESTHETIC MODIFICATIONS OF NEURONAL SODIUM AND POTASSIUM CHANNELS

Daniel S. Duch, Tatyana N. Vysotskaya

VOLATILE ANESTHETIC EFFECTS AT EXCITATORY AMINO ACID RECEPTORS

Jo Ellen Dildy-Mayfield, R. Adron Harris

EFFECTS OF VOLATILE ANESTHETICS ON GABAA RECEPTORS: ELECTRICOPHYSICAL STUDIES

Robert A. Pearce

NEUROCHEMICAL ACTIONS OF ANESTHETICS AT THE GABAA RECEPTORS

Eric Moody, Phil Skolnick

STEREOSELECTIVE EFFECTS OF VOLATILE ANESTHETICS

Eric Moody, Phil Skolnick

EFFECTS OF VOLATILE ANESTHETICS AT NICOTINIC ACETYLCHOLINE RECEPTORS

Pamela Flood


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Molecular Bases of Anesthesia





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