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For most of human history, life expectancy was remarkably stable at about 30-40 years. Within the past 150 years, however, medical advances have virtually doubled that number. The world's elderly population is growing at 2.4% per year, faster than the rest of the population, with disproportionate increases expected to continue as newer and better treatments are found that minimize the disabilities associated with advanced age.
Key to improving the health and quality of life of the elderly is understanding and treating the brain diseases and behavioral disorders that become highly prevalent with age. Geriatric neuropsychiatry is an integrative specialty that draws from many diverse fields, including psychiatry, neurology, neuroscience, and geriatrics. It provides expertise on how to distinguish normal age-related changes from those of disease and disordered brain function.
Edited by two eminent practitioners and educators, this wide-ranging textbook's 41 chapters are divided into five major sections:
* Introduction to Geriatric Neuropsychiatry-Introduces the field, including the epidemiology of aging and its array of interacting and accumulating disadvantages, the neurobiology of aging, and the neurobiological basis of behavior
* Neuropsychiatric Assessment of the Elderly-Describes how to ensure early, accurate diagnoses, using both the fundamental cognitive skills evaluation and the more in-depth neuropsychological evaluation; age-associated memory impairment (AAMI) and its biological bases; anatomic imaging of age-related changes in brain morphology; and the latest imaging techniques that allow visualization of brain function in vivo
* Neuropsychiatric Aspects of Psychiatric Disorders in the Elderly-Covers everything from affective and anxiety disorders, substance abuse, and psychoses that start late in life to sleep disorders, delirium, pain, contemporary personality psychology, mental retardation, and aggression
* Neuropsychiatric Aspects of Neurological Disease in the Elderly-Focuses on diseases such as nondegenerative dementing disorders, Alzheimer's and Parkinson's diseases, hyperkinetic movement disorders, stroke, epilepsy, and traumatic brain injury, concluding with medical illnesses and therapies
* Principles of Neuropsychiatric Treatment of the Elderly-Discusses the effect of age in geriatric neuropsychopharmacology, psychopharmacology, ECT, psychosocial therapies, neuropsychiatry in nursing homes, genetic interventions, rehabilitation, ethical issues, and competency and related forensic issues
Exhaustively researched and annotated, the American Psychiatric Press Textbook of Geriatric Neuropsychiatry, Second Edition provides a definitive core reference for psychiatry and neurology residents, particularly those pursuing a specialty in geriatrics, and for graduate students in psychology, neuropsychology, and related fields.
About The Author:Edward Coffey, M.D., is Professor of Psychiatry (Neuropsychiatry) and Medicine (Neurology), and Chairman of the Kathleen and Earl Ward Chair, Department of Psychiatry at Henry Ford Health System, Detroit Michigan.
Jeffrey L. Cummings, M.D., is Augustus S. Rose Professor of Neurology and Psychiatry and Biobehavioral Sciences and Director of the UCLA Alzheimer's Disease Center at the University of California, Los Angeles, School of Medicine in Los Angeles, California.
Table of Contents:
Contributors
Foreword
Preface
Sect. I Introduction to Geriatric Neuropsychiatry
1 Geriatric Neuropsychiatry 3
2 Epidemiology of Aging 17
3 Neurobiology of Aging 33
4 Neurobiological Basis of Behavior 81
Sect. II Neuropsychiatric Assessment of the Elderly
5 Neuropsychiatric Assessment 109
6 Mental Status Examination 125
7 Neuropsychological Assessment 143
8 Age-Associated Memory Impairment 165
9 Anatomic Imaging of the Aging Human Brain: Computed Tomography and Magnetic Resonance Imaging 181
10 Functional Brain Imaging: Cerebral Blood Flow and Glucose Metabolism in Healthy Human Aging 239
11 Functional Brain Imaging: Functional Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy 267
12 Quantitative Electroencephalography: Neurophysiological Alterations in Normal Aging and Geriatric Neuropsychiatric Disorders 285
Sect. III Neuropsychiatric Aspects of Psychiatric Disorders in the Elderly
13 Mood Disorders 313
14 Late-Life - Onset Psychoses 329
15 Anxiety Disorders 347
16 Substance Abuse 367
17 Sleep Disorders 401
18 Pain 415
19 Delirium 441
20 Contemporary Personality Psychology 453
21 Mental Retardation 463
22 Aggression 477
Sect. IV Neuropsychiatric Aspects of Neurological Disease in the Elderly
23 Nondegenerative Dementing Disorders 491
24 Alzheimer's Disease and Frontotemporal Dementia 511
25 Hyperkinetic Movement Disorders 531
26 Parkinson's Disease and Parkinsonism 559
27 Stroke 601
28 Traumatic Brain Injury 621
29 Epilepsy 655
30 Neoplastic, Demyelinating, Infectious, and Inflammatory Brain Disorders 669
31 Medical Therapies 699
32 Neurobehavioral Syndromes 729
Sect. V Principles of Neuropsychiatric Treatment of the Elderly
33 Geriatric Neuropsychopharmacology: Why Does Age Matter? 749
34 Psychopharmacology 779
35 Electroconvulsive Therapy 829
36 Psychosocial Therapies 861
37 Neuropsychiatry in Nursing Homes 891
38 Genetic Interventions 905
39 Rehabilitation 917
40 Ethical Issues 935
41 Competency and Related Forensic Issues 945
Index 965
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American Psychiatric Press Textbook of Geriatric Neuropsychiatry