G Protein Methods and Protocols: Role of G Proteins in Psychiatric and Neurological Disorders

Author: Ram K. Mishra
Published: July 1997
Publisher: Humana Press
ISBN: 0896034909
Hardcover Book
Number of Pages: 433

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This new work marks a novel departure from books focused narrowly on the physical properties of G proteins in isolation. By providing detailed methods and techniques, this volume's front-line contributors bring out the implications of G protein signal transduction for psychiatric and neurological disorders. Practical and authoritative G Protein Methods and Protocols will surely prove a major practical resource for all neurochemists, neurologists, molecular biologists, pharmacologists, and psychiatrists seeking to study and better understand these disease states.

Table of Contents:

Preface
Contributors
In Vitro Autoradiographic Localization of Receptor-Stimulated [actual symbol not reproducible] Binding in Brain 1
Small-Molecular-Weight G Proteins: Characterization and Significance 29
G Proteins in the Etiology and Treatment of Mental Disorders 53
G Protein [alpha]- and [beta][gamma]-Subunits as Possible Mediators of Dopamine-D1:D2 Receptor Ligand Binding Interactions 81
Modulation of G Proteins in Rat Striatum by Neuroleptic Drugs and a Peptidomimetic Analog of Pro-Leu-Gly-NH[subscript 2] 119
G Proteins and Animal Models of Parkinson's Disease 139
Protein Kinase C as a Modulator of 5-HT1A and Dopamine-D2 Receptor Signaling 163
Molecular Mechanisms of Opiate Addiction in the Nucleus Accumbens: Morphine Regulation of G Proteins 189
G Protein-Linked Opioid Receptors 207
G Protein-Coupled Melatonin Receptors 223
G Proteins in the Pathophysiology and Treatment of Mood and Anxiety Disorders 283
Determination of Adenosine Receptor-G Protein Coupling: Significance for Psychiatric and Neurological Disorders 327
G Proteins and Mood Disorders 353
G Proteins in the Medial Temporal Lobe in Schizophrenia 379
G Protein Abnormalities in Schizophrenia 393
Index 419

Click to compare book prices for G Protein Methods and Protocols: Role of G Proteins in Psychiatric and Neurological Disorders G Protein Methods and Protocols: Role of G Proteins in Psychiatric and Neurological Disorders

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