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Preface
Contributors
1 Estrogen Receptor in Mammary Gland Physiology 1
2 Multiple Facets of Estrogen Receptor in Human Breast Cancer 17
3 Progesterone Receptors in Normal and Neoplastic Breast 35
4 Pathogenesis of Estrogen Receptor-Positive and -Negative Breast Cancer 49
5 Regulation of EGFR and ERBB2 Expression by Estrogen Receptor in Breast Cancer 69
6 Tamoxifen and Other Antiestrogens in Prevention and Therapy of Breast Cancer 79
7 Prolactin in Human Breast Cancer Development 101
8 Human Chorionic Gonadotropin in Breast Cancer Prevention 121
9 Epidermal Growth Factor-Related Peptides in Endocrine Neoplasias 137
10 Insulin-Like Growth Factors and Endocrine Neoplasia 193
11 Insulin-Like Growth Factor Binding Proteins in Endocrine-Related Neoplasia 215
12 Fibroblast Growth Factors and Their Receptors in Breast and Prostate Cancer 237
13 Steroid Receptors in Prostate Cancer Development and Progression 255
14 Type I Family Growth Factor Receptors and Their Ligands in Prostate Cancer 277
15 Hormonal Manipulation of Prostate Cancer 293
16 Endocrinology of Epithelial Ovarian Cancer 313
17 Molecular Pathogenesis of Endometrial Cancer: The Role of Tamoxifen 325
18 Structure and Function of BRCA Genes 337
19 Role of Apoptosis and its Modulation by Bcl-2 Family Members in Breast and Prostate Cancer 353
20 Transcriptional Coactivators in Cancer 373
Index 383