Biotherapeutic Agents and Infectious Diseases

Author: Gary W. Elmer
Published: December 1998
Publisher: Humana Press
ISBN: 0896036472
Hardcover Book
Number of Pages: 316

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The term "biotherapeutic agents" is used to describe microorganisms having a therapeutic effect in humans. This book discusses the use of whole, living microorganisms with in vivo antagonistic activities against specific pathogens as a modality for the prevention and treatment of infectious diseases. The goal of this approach is the restoration or enhancement of the normal protective ability of the body to resist pathogen establishment and proliferation.

Table of Contents:

Preface
Contributors
1 Quality Control and Regulatory Issues for Biotherapeutic Agents 1
2 Mechanisms of Action of Biotherapeutic Agents 27
3 Pharmacokinetics of Biotherapeutic Agents 47
4 Influences on the Normal Microbial Flora 85
5 Immunological Effects of Biotherapeutic Agents 121
6 Biotherapeutic Agents in the Prevention of Antibiotic-Associated Diarrhea 145
7 Biotherapeutic Agents for Clostridium difficile-Associated Disease 159
8 Biotherapeutic Agents in the Management of Pediatric Diarrheal Disease 195
9 Biotherapeutic Agents and Adult Diarrhea 207
10 Biotherapeutic Agents as Therapy for Vaginitis 221
11 Biotherapeutic Agents to Prevent Cystitis in Women 245
12 Risks of Biotherapeutic Agents 263
13 Future Directions for Research on Biotherapeutic Agents: Contribution of Genetic Approaches on Lactic Acid Bacteria 269
Index 305

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