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Preface
List of Color Plates
Contributors
I Anemia and Other Cytopenias 1
1 A Practical Approach to the Diagnosis of Anemia 3
2 Specific Anemia Syndromes and Their Management 21
3 The Thalassemia Syndromes and the Hemoglobinopathies 41
4 Sickle Cell Disorders 65
5 Practical Aspects in the Diagnosis and Management of Aplastic Anemia 83
6 Differential Diagnosis of Neutropenia 93
7 Causes and Management of Isolated Thrombocytopenia 105
II Primary and Secondary Myeloproliferative Disorders 117
8 An Approach to the Patient With Erythrocytosis 119
9 Differential Diagnosis and Management of Thrombocytosis 129
10 Chronic Myeloproliferative Diseases: Polycythemia Vera and Agnogenic Myeloid Metaplasia 137
11 An Approach to the Patient With Myelodysplasia 149
12 The Eosinophil and Eosinophilia 161
III Leukemias and Hematopoietic Stem Cell Transplantation 173
13 Leukocytosis and the Chronic Leukemias 175
14 Acute Leukemia 193
15 Blood and Marrow Transplantation 209
IV Lymphoid and Plasma Cell Disorders 229
16 Lymphadenopathy 231
17 Hodgkin's Disease and Non-Hodgkin's Lymphoma 241
18 An Evaluation of Patients With Monoclonal Gammopathies 255
19 Multiple Myeloma and Related Disorders 269
V Thrombotic and Bleeding Disorders 289
20 An Overview of the Hemostatic System and Interpretation of Common Screening Coagulation Tests 291
21 Bleeding Disorders: An Overview and Clinical Practice 303
22 Thrombogenesis and Thrombotic Disorders 317
VI Miscellaneous Topics in Hematology 337
23 Transfusion Medicine: Practical Issues 339
24 Hereditary Hemochromatosis: A Disease for All Physicians 351
25 Hematologic Manifestations of HIV Disease 365
26 Hematopoietic Growth Factors in Clinical Practice 371
27 A Primer of Chemotherapy 379
28 An Approach to Porphyria 407
29 Ethical Issues in the Care of Patients With Hematologic Diseases 415
30 Statistical Methods Frequently Used in Hematology Research 431
Index 451