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Preface v
Contributors ix
1 The Glucocorticoid Domain in the Lung and Mechanisms of Action 1
2 Fetal Responses to Glucocorticoids 45
3 Cyclic Adenosine Monophosphate and Glucocorticoid Regulation of Surfactant Protein-A Gene Expression 59
4 Hormonal Regulation of Surfactant Protein-B and Surfactant Protein-C Gene Expression in Fetal Lung 81
5 Glucocorticoid Regulation of Fatty Acid Synthase in Fetal Lung 91
6 The Genetics of Glucocorticoid-Regulated Embryonic Lung Morphogenesis: A First Approximation of the Epigenetic Rules 105
7 Corticotropin-Releasing Hormone and the Lung 125
8 Sex Differences in Fetal Lung Development: Biology, Etiology, and Evolutionary Significance 141
9 Retinoids and Lung Development 161
10 Insulin and Lung Development 181
11 The Insulin-like Growth Factor System and Lung 201
12 Platelet-Derived Growth Factor and Lung Development 225
13 Transforming Growth Factor-[beta] Receptor Signaling and Lung Development 241
14 Transgenic Mouse Models for the Study of Growth Factor Signaling During Lung Morphogenesis 255
15 Parathyroid Hormone-Related Protein 269
16 Role of Neuroendocrine Cells in Fetal and Postnatal Lung 299
Index 337