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Preface
Dedication
Contributors
1 Normal Mechanisms for Self-Tolerance 1
2 Immunoregulation in Experimental Autoimmune Endocrine Disease 31
3 The Genetic Susceptibility to Type 1 (Insulin-Dependent) Diabetes Mellitus and the Autoimmune Thyroid Diseases: From Epidemiological Observations to Gene Mapping 57
4 Experimental Models for Autoimmune Thyroid Disease: Recent Developments 91
5 Animal Models for Insulin-Dependent Diabetes Mellitus 113
6 The Epidemiology of Autoimmune Thyroid Disease 141
7 Sex Hormones and Immune Responses 163
8 Autoantigens in the Autoimmune Endocrinopathies 183
9 The Immunology of Human Autoimmune Thyroid Disease 217
10 Thyroid-Associated Ophthalmopathy and Dermopathy 245
11 Postpartum Autoimmune Endocrine Syndromes 271
12 Etiology and Pathogenesis of Human Insulin-Dependent Diabetes Mellitus 293
13 Autoimmune Adrenocortical Failure 309
14 Autoimmune Hypophysitis 337
15 The Polyglandular Autoimmune Syndromes 349
16 Autoimmune Endocrinopathies in Female Reproductive Dysfunction 365
17 Immunotherapy and Prevention of Autoimmune Endocrinopathies 393
Index 419