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Preface
Contributors
1 The Epidemiology of Renal Cell Carcinoma 1
2 The Pathology of Renal Neoplasms 15
3 Immunologic Response to Renal Cell Carcinoma 39
4 Molecular Mechanisms of Immune Dysfunction in Renal Cell Carcinoma 63
5 Molecular Genetics of Renal Cell Carcinoma 79
6 Screening for Renal Cell Carcinoma 93
7 Renal Cell Carcinoma: Diagnosis and Staging 111
8 Paraneoplastic Syndromes in Renal Cell Carcinoma 135
9 Prognostic Factors in Metastatic Renal Cell Carcinoma 147
10 Radical Nephrectomy and Nephron-Sparing Surgery for Localized Renal Cell Carcinoma 163
11 Management of Patients with Renal Cell Carcinoma and Vena Caval Thrombi 173
12 Laparoscopic Surgery for Renal Cell Carcinoma 189
13 Adjuvant Therapy for Renal Cell Carcinoma 203
14 The Role of Nephrectomy and Metastasectomy for Advanced Renal Cell Carcinoma 215
15 Management of Pulmonary Metastases in Renal Cell Carcinoma Patients 229
16 Management of Skeletal Metastases in Renal Cell Carcinoma Patients 239
17 Management of Central Nervous System Metastases in Renal Cell Carcinoma Patients 269
18 Chemotherapy for Metastatic Renal Cell Carcinoma (RCC) 283
19 Interleukin-2 in Metastatic Renal Cell Carcinoma 301
20 Role of Interferon in Metastatic Renal Cell Carcinoma 319
21 Combination Therapy for Treatment of Advanced Renal Cell Carcinoma 331
22 Monoclonal Antibodies in Advanced Renal Cell Carcinoma 343
23 Adoptive Immunotherapy in Renal Cell Carcinoma 359
24 Antiangiogenic Agents and Strategies in Renal Cell Carcinoma 381
25 Therapy for Patients with Uncommon Histologic Varieties of Renal Cell Carcinoma 397
26 Palliation in Patients with Advanced Renal Cell Carcinoma: The Interface with Antineoplastic Therapy 407
Index 425