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Table of Contents:

List of principal authors
Preface: Kidney disease-inducing monoclonal immunoglobulins
1 Physiopathology of malignant B cell lymphoproliferations 3
2 Immunoglobulin synthesis and secretion 12
3 Immunoglobulin decreased solubility diseases: pathologies of the V domains? 29
4 Megalin, cubilin and immunoglobulin light chains: receptor-mediated uptake of light chains in kidney proximal tubule 37
5 Pathophysiology of myeloma kidney 53
6 Myeloma cast nephropathy: clinical presentation 61
7 New therapeutic approaches for the myeloma patient with and without renal failure 65
8 Adult Fanconi's syndrome due to monoclonal immunoglobulin light chains: an underdiagnosed disease with unexpected clinical and pathologic heterogeneity 75
9 Monoclonal immunoglobulin light chains associated to Fanconi's syndrome 87
10 Ultrastructural pattern and classification of renal monoclonal immunoglobulin deposits 95
11 Morphological aspects in light chain deposition disease 121
12 Renal monoclonal immunoglobulin deposition disease (MIDD): the Columbia experience 130
13 Monoclonal cryoglobulinemia kidney 145
14 Fibrillary glomerulonephritis: defining the disease spectrum 152
15 Glomerulonephritis with organized immunoglobulin deposits: fibrillar and microtubular deposits are associated with distinct immunological features 163
16 Clinical features and management of amyloidosis 187
17 Fibrillogenesis and therapy of amyloidosis: an equilibrium approach 203
18 Immunoglobulin light chain amyloidosis and the kidney 215
19 Treating primary systemic amyloidosis with stem cell transplantation: outcomes in renal amyloidosis 227
20 Prognostic factors for survival and response after high-dose therapy and autologous stem cell transplantation in systemic AL amyloidosis: a report on 21 patients
21 Presentation of the French multicentre randomized trial comparing intensive and conventional treatment for AL amyloidosis 240
22 Amyloidosis: Round Table 243
Oral communications 250
Poster communications 261