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Table of Contents:

Preface 1
Pathology of prostate cancer 3
Prostate cancer susceptibility genes: Many studies, many results, no answers 19
Molecular profiling in prostate cancer 29
Chromosomal deletions and tumor suppressor genes in prostate cancer 37
Role of eicosanoids in prostate cancer progression 59
Contribution of the androgen receptor to prostate cancer predisposition and progression 71
Regulation of apoptosis in prostate cancer 89
On the role of cell surface carbohydrates and their binding proteins (lectins) in tumor metastasis 109
Metastasis suppression in prostate cancer 143
The urokinase-type plasminogen activator system in prostate cancer metastasis 151
Angiogenesis in prostate cancer: Biology and therapeutic opportunities 161
Integrins and prostate cancer metastases 185
Prostate carcinoma skeletal metastases: Cross-talk between tumor and bone 197
Signal transduction targets in androgen-independent prostate cancer 215
The diet, prostate inflammation, and the development of prostate cancer 227
Prostate cancer diagnosis, staging and survival 241
Surgery for prostate cancer: Rationale, technique and outcomes 253
The future of cancer imaging 269
Antisense therapy: Current status in prostate cancer and other malignancies 303
Antiangiogensis therapeutic strategies in prostate cancer 317
Chemoprevention of prostate cancer 331
Prostate brachytherapy 345
Fast neutron irradiation for prostate cancer 351
Prostate cancer gene therapy: Past experiences and future promise 357
Vitamin D-related therapies in prostate cancer 367
Osteoporosis and other adverse body composition changes during androgen deprivation therapy for prostate cancer 379