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Immunology of Infectious Disease

Author: Stefan H. Kaufmann
Published: January 2002
ISBN: 1555812147
Hardcover Book
Number of Pages: 520
 
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Immunology of Infectious Disease


This volume offers an integrated view of the principal aspects of immune response to all types of infectious agents, with an emphasis on the immune system primarily as a host defense system. Sixty-four specialists from Europe, the U.S. and Canada contribute 30 chapters organized into sections on the pathogens, the anti-infective immune response, innate immunity, acquired immunity, pathology, evasion and latency, immunogenetics, and immune intervention. For microbiologists interested in pathogenesis and immunology; clinicians interested in immunology, virology, vaccine development, infectious diseases, bacteriology, parasitology, pathology, and cell biology; and immunologists desiring greater knowledge of infectious diseases and their causative agents.


Table of Contents:


Contributors
Preface
Introduction 1
1 Overview of the Bacterial Pathogens 5
2 Overview of the Fungal Pathogens 25
3 Overview of the Parasitic Pathogens 39
4 Overview of the Viral Pathogens 53
5 Evolution of the Host Defense System 67
6 Phagocytes and Anti-Infective Immunity 79
7 Innate Immunity in Bacterial Infections 93
8 Defensins and Cathelicidins: Antimicrobial Peptide Effectors of Mammalian Innate Immunity 105
9 Innate Immunity to Parasitic Infections 111
10 Innate Immunity and Fungal Infections 127
11 Innate Immunity and Viral Infections 139
12 The Th1/Th2 Paradigm in Infections 163
13 Immunological Memory and Infection 175
14 Regional Immune Response to Microbial Pathogens 191
15 Acquired Immunity against Bacteria 207
16 Acquired Immunity against Fungi 223
17 Adaptive Immune Effector Mechanisms against Intracellular Protozoa and Gut-Dwelling Nematodes 235
18 Acquired Immunity against Viral Infections 247
19 Autoimmunity as a Consequence of Infection 269
20 Pathology and Pathogenesis of Bacterial Infections 281
21 Pathology and Pathogenesis of Parasitic Disease 293
22 Pathology and Pathogenesis of Virus Infections 307
23 Bacterial Persistence: Strategies for Survival 331
24 Viral Immune Evasion 357
25 Immune Evasion by Parasites 379
26 Immunogenetics of the Host Response to Bacteria and Parasites in Humans 395
27 Immunogenetics of the Host Response to Bacteria in Mice 407
28 Immunogenetics of the Host Response to Viral Infections 421
29 Immune Intervention in Tuberculosis 439
30 Immune Intervention in AIDS 453
Index 479


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Immunology of Infectious Disease





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